General Manager jobs in United Arab Emirates

Working week: 5.5 days

Working Hours: Monday to Friday – 9 am to 6 pm and Saturday - 9 am to 1 pm

Salary Ranges: Monthly Salary: S$16,500 to S$18,000

Summary:

The CEO will establish and run Singapore’s first integrated longevity-focused translational hub for the Company, overseeing every stage from hypothesis-driven discovery through IND-ready manufacturing for age-modifying therapeutics and diagnostics. Success demands a rare blend of deep geroscience know-how, cross-jurisdictional regulatory mastery, and venture-financing experience that aligns with the parent group’s global IP and capital-market strategy.

Key Responsibilities:

A. Scientific & Clinical Strategy

• Draft and execute a 5-year programme that converts hallmarks-of-ageing research into first-in-human candidates.
• Integrate multi-omics, AI-driven target discovery, and large-animal longevity models within GLP workflows.
• Synchronise Singapore R&D with parallel GMP efforts in the UK and US.

B. Capital Formation & Governance

• Lead equity and convertible-note rounds totalling > US$5 million within 18 months.
• Structure cross-border IP-holding and grant-funding vehicles to maximise Singapore RIE incentives and Section 13R tax benefits.
• Chair the Audit & Risk Committee; oversee quarterly board packs.

C. Operations & Compliance

• Commission a BSL-2/ISO-7 cleanroom and ensure readiness for HAS and EMA inspections.
• Implement ISO-27001 aligned data-integrity systems for multi-site pre-clinical studies.
• Maintain 100% adherence to MOM fair employment guidelines and TAFEP best practices.

D. Talent & Culture

• Build a lean team (< 15 FTEs in year 1) spanning bioinformatics, CMC, clinical operations, and finance.
• Introduce a 24-month rotational leadership development plan and continuous-learning stipends tied to milestone KPIs.
• Negotiate ecosystem partnerships with ASTAR institutes, local CDMOs, and Temasek-linked venture funds. Act as company spokesperson at global geroscience consortia and Singapore Week of Innovation & Technology (SWITCH).

Job Requirements:

A. Experience

• > 8 years senior leadership (VP, GM, or C-suite) in venture-backed therapeutics or diagnostic start-ups.
• Demonstrable full-cycle advancement of at least one aging-modulation asset to IND or CE-IVD/510(k) filing.
• Hands-on responsibilities for raising > US$5 million in external capital.
• Direct oversight of multi-jurisdictional regulatory filings (HSA plus at least one of GDA/EMA/MHRA).

B. Technical Exposure

• Working familiarity with geroprotective modalities (e.g., NAD+ boosters, senolytics, epigenetic reprogramming, telomere maintenance) and associated CMC challenges (viral-vector or LNP delivery, sterile-fill finish, stability).
• Competence in drafting data-room materials for longevity VC due diligence and sovereign-wealth co-investment.

C. Leadership & Soft Skills

• Strategic thinker capable of translating complex biology into investable milestones under tight capital constraints.
• Adept at navigating matrixed, cross-time zone governance structures and high-velocity change environments.
• Uncompromising professional ethics and risk-management discipline.

D. Mobility

• Willing to undertake frequent travel (up to 40%) to the UK, EU, and US for board meetings, clinical-site qualification, and partner negotiations.
• After-hours availability for global time-zone calls, coordination with Europe/US, and readiness for urgent board interventions.