Director Of Sales jobs in United Kingdom

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) a serious liver disease that can progress to cirrhosis liver failure need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose : leading the fight against MASH.

Madrigals medication Rezdiffra (resmetirom) is a once-daily oral liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic inclusive and high-performing culture that values scientific excellence operational rigor and collaboration. To support our continued growth we are strengthening our workforce strategy to ensure we have the right talent at the right time in the right way.

The UK Marketing Lead is a key member of the UK Commercial Team and is responsible for shaping and executing the local brand strategy to support the successful launch of Rezdiffra and sustained market growth. This role leads the development of integrated marketing plans ensures flawless execution in the field and partners closely with cross-functional teams to deliver high-impact commercial outcomes.

The ideal candidate brings deep specialty launch experience strong strategic acumen and a hands‑on approach to driving performance in fast‑evolving markets.

S / he will demonstrate patient focus in every decision act with an owner mindset champion innovation and foster collaboration to drive impact and advance Madrigals purpose of leading the fight against MASH.

• Lead the development and execution of the country brand strategy aligning with global priorities.
• Build a comprehensive launch plan tailored to local market dynamics competitive conditions and patient needs.
• Translate scientific and clinical insights into compelling differentiated value propositions and customer narratives.
• Serve as the launch champion for the country driving cross-functional alignment readiness and performance tracking.
• Develop evidence-based brand positioning messaging platforms and promotional materials.
• Partner with medical market access and sales to ensure integrated compliant launch execution.
• Design and implement omnichannel customer engagement strategies for specialists and other key stakeholders.
• Identify market barriers and opportunities to shape the ecosystem in support of optimal patient outcomes.
• Generate actionable insights through proactive customer engagement analytics and field collaboration.
• Co‑lead the cross‑functional brand team ensuring strong communication across commercial medical regulatory compliance and access teams.
• Collaborate closely with international and global teams to ensure alignment and pull‑through of strategy and tools.
• Partner with the sales organization to deliver effective field team training messaging pull‑through and performance monitoring.
• Monitor brand performance using KPIs and insights; adjust plans as needed based on evolving data.
• Manage the brand budget and ensure efficient compliant deployment of resources.
• Provide regular updates on strategy launch progress and business risks to local leadership.

• Strategic analytical thinker with the ability to translate insights into clear plans and impactful execution.
• Strong communicator skilled at engaging senior stakeholders and influencing without authority.
• Collaborative partner who builds trust across commercial medical and access functions.
• Highly organized with strong project management capabilities and attention to detail.
• Comfortable operating in agile fast‑paced and high‑accountability environments.
• Hands‑on marketer who balances strategic leadership with operational excellence.
• Demonstrated ability to lead make decisions and maintain momentum in conditions of uncertainty and ambiguity.

• Bachelors or Masters degree in life sciences business marketing or a related field.
• 8 years of pharmaceutical commercial or marketing experience including specialty launch experience at the country level.
• Proven experience developing and executing brand and launch strategies that deliver strong business outcomes.
• Demonstrated capability in customer engagement omnichannel strategy and insights generation.
• Strong scientific aptitude and ability to translate complex clinical data into clear compelling messaging.
Experience leading and coordinating cross‑functional teams.
• Excellent communication collaboration and project management skills.
• Fluency in English and already authorized to work in the United Kingdom.

All full‑time employees receive equity which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance we empower employees to think like owners giving them a stake in the organization.

Full‑time employees are also eligible for comprehensive benefits including flexible paid time off medical dental vision and life / disability insurance and 401(k) offerings (i.e. traditional Roth and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance legal services and other addition we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal state and local laws.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance please contact

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications merit and business need. Applicants will receive consideration for employment without regard to race ethnicity color religion sex gender identity sexual orientation national origin age disability protected veteran or disabled status or other characteristic protected by applicable federal state or local law.

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.

Employment Type: Full‑Time