Pharmaceutical jobs in South Africa

• Implement, maintain and improve the local QMS in alignment with global and regulatory standards.

• Lead management reviews, internal audits, quality improvement projects and compliance monitoring activities.

• Ensure full compliance with Good Manufacturing Practice (GMP), Good Distribution Practice (GDP), GxP and Pharmacy Act requirements.

• Support SAHPRA inspections, internal and external audits including preparation, hosting and CAPA management.

• Act as Deputy to the Responsible Pharmacist in their absence and assist in the performance of all regulatory responsibilities as defined under the Pharmacy Act.

• Ensure that all activities related to the procurement, storage, handling, distribution and quality control of pharmaceutical products and medical devices are conducted in accordance with legal and ethical standards.

• Monitor and ensure compliance with conditions of registration, licenses and permits (e.g. SAHPRA SAPC).

• Maintain oversight of batch release, recall processes and documentation as required by the South African regulatory framework.

• Ensure the proper recording and reporting of product complaints and adverse events in collaboration with pharmacovigilance and regulatory teams.

• Liaise with the SAPC and other authorities as needed.

• Manage SOPs, policies and other controlled documents. Oversee document lifecycle archival and version control as per the corporate guidelines.

• Lead change control processes, ensuring all proposed changes are assessed for quality and compliance impact.

• Ensure product quality compliance across all stages from receipt to final distribution.

• Review and approve quality records, deviations, non-conformances and batch documentation.

• Qualify and audit external service providers (e.g. transporters, warehousing, contract labs).

• Ensure suppliers adhere to quality agreements and meet performance expectations.

• Ensure the TPI are operating in accordance with local regulatory requirements and applicable licenses.

• Supervise the compliance with contractual and quality agreements including product handling, storage, distribution and documentation standards.

• Undergo regular performance assessments, quality audits and risk evaluations.

• Report and manage product complaints, deviations and quality incidents in a timely and compliant manner.

• Ensure clear and effective communication channels between the company and third-party partners to support product quality and patient safety.

• Lead the implementation and periodic review of Quality/Technical Agreements with all third-party distributors.

• Establish and maintain GxP training programs for all relevant staff.

• Ensure personnel involved in the handling of medicines and medical devices are trained and competent.

• Lead quality risk assessments and implement risk mitigation strategies.

• Collaborate with cross-functional teams to proactively address quality concerns.

• Support local pharmacovigilance and product recall activities in compliance with regulatory requirements.

• Participate in mock recalls and coordinate timely execution of recall procedures when needed.

• Prepare and communicate quality metrics and reports to management and global quality teams.

• Escalate quality or compliance issues to senior leadership as necessary.

• Bachelor of Pharmacy (BPharm) and registration with the South African Pharmacy Council (SAPC) is mandatory.

• Minimum 3 years of experience in pharmaceutical quality management or regulatory compliance.

• Strong knowledge of SAHPRA regulations, Pharmacy Act, GMP, GDP and GxP standards.

• Previous experience acting as or supporting a Responsible Pharmacist is an advantage.

• Familiarity with multinational/matrix environments is preferred.

Required Experience: Manager

Key Skills: Computer Science, Graduate Engineering, Interior Design, ASP.NET, Event Planning

Employment Type : Full-Time

Experience: years

Vacancy: 1