Project Manager Senior jobs in United Kingdom

Are you ready to make a significant impact in the world of indirect tax? AstraZeneca is on the lookout for a seasoned VAT professional to lead and deliver initiatives across our global indirect tax agenda. This role is pivotal in managing our VAT compliance, risk management, governance, and transformation programs. You'll collaborate with senior leaders and cross-functional teams to ensure compliance, optimize cash flow, and drive growth through practical VAT advice. Are you up for the challenge?

• Strategic management and governance : Lead AstraZeneca’s multi-jurisdictional indirect tax compliance, risk management, and transformation initiatives, ensuring alignment with Group objectives.
• Foreign indirect tax compliance : Oversee foreign indirect tax compliance obligations, navigating complex regulatory frameworks and resolving issues effectively.
• Global indirect tax strategy : Contribute to the development and execution of AstraZeneca’s global indirect tax strategy, driving sustainable value creation.
• Risk and controls : Develop and maintain comprehensive indirect tax risk management frameworks, including governance over controls testing and continuous improvement.
• VAT audits and controversy : Lead complex VAT audits and controversies, fostering constructive relationships with tax authorities.
• Supply chain advisory : Provide guidance on indirect tax impacts for commercial and clinical operations supply chains.
• Business partnering : Offer timely VAT guidance to partners on business-as-usual and new operations, supporting business initiatives proactively.
• Complex technical advisory : Research and advise on intricate VAT issues such as cross-border supply rules and multi-jurisdiction reorganizations.
• Digital transformation : Support enterprise transformation initiatives by integrating advanced analytics, AI, and tax technology for enhanced compliance and efficiency.
• Process excellence : Find opportunities for process improvement and harmonization.
• Accounts Payable and Purchasing Organization (APPO) support : Provide expert indirect tax support to AstraZeneca’s APPO community, resolving technical queries.
• Outsource provider management : Collaborate with compliance outsource providers to drive improvements in compliance, data quality, and efficiencies.
• Risk escalation and coordination : Identify and elevate compliance risks, ensuring holistic tax outcomes across direct tax, customs / duties, and transfer pricing.
• Contribute to the development of the wider tax function through coaching and mentoring junior team members, champion Diversity and Inclusion strategies.

• Education : Degree in accounting, finance, law, or related field. Professional qualification preferred (, CTA, CPA, ACA, or equivalent).
• Experience : Demonstrable post-qualification experience in multi-jurisdictional VAT / indirect tax within a multinational or Big Four / major advisory, with consistent record across compliance, advisory, and controversy.
• Technical expertise : Deep knowledge of EU VAT (strong preference for UK / SE / IE / other EU member experience) and US foreign indirect tax obligations (, VAT / GST for US outbound activity and registrations outside the US), place of supply rules, chain transactions, E-invoicing / real-time reporting, and tax determination engines.
• Transformation : Demonstrated experience delivering tax technology and ERP-enabled change (, SAP S / 4HANA, GTS, Vertex / ONESOURCE, APPO), data governance, and process optimization.
• Personal attributes : Strategic thinker with a hands‑on approach, high ownership, resilience, and continuous improvement outlook.

When we put unexpected teams in the same room, we unleash ambitious thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and daring world.

AstraZeneca offers an environment where innovation thrives. With a commitment to delivering more medicines to patients quickly and affordably, we are backed by investment and leadership that supports personal dedication and out-of-the-box thinking. Our inclusive network fosters collaboration among diverse teams who share a passion for impacting lives positively. Here, you can broaden your knowledge and skills while contributing to a global mission that drives commercial viability and scales delivery rapidly.

Ready to take your career to the next level? Apply now to join AstraZeneca's dynamic team!

24-Nov-2025

23-Nov-2025

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments / accommodations to help all candidates to perform at their best. If you have a need for any adjustments / accommodations, please complete the section in the application form.