Postdoctoral Fellow in Advanced Mueller Polarimetric Imaging for In Vivo Biomedical Applications

Laboratoire de Physique des Interfaces et des Couches Minces (LPICM), UMR CNRS/École Polytechnique,; France; Sur place; EUR 38 000 - 45 000; Plein temps

Résumé du poste

A leading research laboratory in France is seeking a post-doctoral researcher to develop advanced optical systems for medical imaging. The role involves designing a high-performance prototype, optimizing optical techniques, and collaborating with clinical teams. Candidates should have a PhD in a relevant field and proficiency in programming. This is a full-time, temporary position based in Palaiseau.

Qualifications

• Strong knowledge of physics and algebraic calculus.
• Methodical, rigorous, creative, and challenge-oriented mindset.
• Ability to thrive in a multidisciplinary environment.

Responsabilités

• Design and develop a high-performance MPC prototype for medical applications.
• Optimize optical systems for rapid acquisition and high-resolution imaging.
• Test and optimize the MPC in vivo.

Connaissances

Optical instrumentation

Data processing

Machine/deep learning

Programming (MATLAB, Python, C/C++, LabVIEW)

Fluency in English

Formation

PhD in Physics, Optics, Biomedical Engineering or related field

Description du poste

Overview

Organisation/Company Laboratoire de Physique des Interfaces et des Couches Minces (LPICM), UMR CNRS/École Polytechnique. Research Field Physics Engineering. Researcher Profile First Stage Researcher (R1). Country France. Application Deadline 26 Oct 2025 - 22:00 (UTC). Type of Contract Temporary. Job Status Full-time. Offer Starting Date 1 Nov 2025. Is the job funded through the EU Research Framework Programme? Not funded by a EU programme. Is the Job related to staff position within a Research Infrastructure? No.

Offer Description

The position unfolds in three phases, within a multidisciplinary team involving image processing labs (e.g., CMAP) and French hospitals (e.g., CHU Kremlin-Bicêtre, Hôpital Foch, Institut Mutualiste Montsouris, Institut Gustave Roussy).

1. Phase 1: Design and develop a high-performance MPC prototype adapted to medical constraints. Key tasks include:

• Optimizing the illumination and detection systems, along with associated optics, to maximize signal-to-noise ratio, ensure rapid acquisition (minimizing motion artifacts from patient movements like breathing or heartbeat), and achieve high-resolution macroscopic images across visible to near-infrared wavelengths. Include options for precision magnification without signal loss.
• Creating a compact, miniaturized polarimetric module adaptable to commercial colposcopes, integrating components like polarizers, waveplates, liquid crystals, and spectral filters.
• Developing a user-friendly calibration system for clinicians.
• Testing and optimizing the MPC in vivo under real conditions.
• Contributing to image post-processing (denoising, Mueller matrix calculation/decomposition) and AI-based diagnostic algorithms using machine/deep learning.

The primary challenge will be to deliver practitioner-relevant cervical images in under 0.5 seconds in vivo, including acquisition, processing, and diagnostics.

The post-doctoral fellow will work in close collaboration with an embedded systems engineer developing the software and electronics for the new MPC prototype, and a PhD student creating and testing automated diagnostic algorithms using unique in-vivo databases from clinical trials launched by the LPICM in collaboration with several hospitals.

1. Phase 2: Adapt the optics to incorporate complementary techniques (e.g., Speckle, OCT, Fluorescence) for innovative multimodal, multiscale cervical analysis in vivo.
2. Phase 3 (Extension): Modify optics for other medical imaging systems, such as polarimetric endoscopes.

Advanced expertise in optical instrumentation, measurements on complex systems, data processing, and physical modeling.

Strong knowledge of physics and algebraic calculus.

Proficiency in programming complex measurement systems, with in-depth experience in languages like MATLAB, Python, C/C++, and LabVIEW.

Basic understanding of electronics and embedded systems.

Methodical, rigorous, creative, and challenge-oriented mindset.

Ability to thrive in a multidisciplinary environment, integrating diverse expertise.

Excellent interpersonal and communication skills.

Fluency in English.

Candidates should hold a PhD in Physics, Optics, Biomedical Engineering, or a related field.

Prior experience in biomedical optical imaging is highly valued.

Work Location(s)

Number of offers available: 1

Company/Institute: Laboratoire de Physique des Interfaces et des Couches Minces (LPICM), UMR CNRS/École Polytechnique

Country: France

City: Palaiseau