Principal Programmer

ICON Strategic Solutions; South Africa; On-site; ZAR 300 000 - 400 000; Full time

Job summary

A leading healthcare intelligence organization in South Africa is seeking a Principal Programmer to analyze clinical trial data and support statistical processes. The successful candidate will have 7+ years of experience in statistical programming, particularly with R and SAS, and a degree in a related field. Responsibilities include developing statistical programs, ensuring compliance with regulatory standards, and contributing to process improvements. Competitive salary and benefits offered.

Benefits

Various annual leave entitlements

Health insurance offerings

Competitive retirement planning

Global Employee Assistance Programme

Life assurance

Flexible country-specific optional benefits

Qualifications

• 7+ years' experience in statistical programming in a clinical research or pharmaceutical setting.
• Experience with R programming and oncology are essential.
• Strong proficiency in SAS programming, with a solid understanding of statistical concepts.

Responsibilities

• Developing and validating programs for statistical analysis and reporting.
• Generating ADaM datasets and tables using R programming.
• Acting as lead programmer on multiple complex studies.

Skills

Statistical programming

R programming

SAS programming

Analytical thinking

Problem-solving

Communication

Education

Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science

Job description

Principal Programmer

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

We are currently seeking a Principal Programmer to join our diverse and dynamic team. As a Principal Programmer at ICON, you will play a crucial role in analyzing clinical trial data and supporting the statistical analysis process to ensure high-quality results. You will contribute to the success of our clinical studies by developing and validating statistical programs, collaborating with biostatisticians, and ensuring compliance with regulatory standards.

What You Will Be Doing:

• Developing and validating programs for statistical analysis and reporting of clinical trial data.
• Generating ADaM datasets and tables, listings and figures, using R programming.
• Acting as lead programmer on multiple complex studies with minimal supervision.
• Liaising with the FSP sponsor in regular meetings and for ad-hoc updates.
• Collaborating with biostatisticians to define analysis plans and statistical methods to be applied to clinical data.
• Performing quality control checks on statistical outputs and ensuring accuracy and consistency in reporting.
• Assisting in the preparation of statistical reports, presentations, and publications for regulatory submissions.
• Contributing to process improvements by identifying efficiencies in programming practices and methodologies.

Your Profile:

• Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, or a related field.
• 7+ years' experience in statistical programming in a clinical research or pharmaceutical setting.
• Experience with R programming and oncology are essential.
• Strong proficiency in SAS programming, with a solid understanding of statistical concepts and methodologies.
• Excellent analytical and problem‑solving skills, with a keen attention to detail.
• Strong communication skills, with the ability to work collaboratively in a team environment and effectively convey complex information.

What ICON can offer you:

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well‑being and work‑life balance opportunities for you and your family.

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24‑hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well‑being.
• Life assurance
• Flexible country‑specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here.

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply.