IRSN
Groupe KILOUTOU
Vitalis Médical
EDF power solutions
EDF power solutions
Connect with headhunters to apply for similar jobsCrédit Agricole SA
Crédit Agricole SA
Mercato de l'emploi
Crédit Agricole SA
Crédit Coopératif
MA (Montreal Associates)
Une organisation scientifique en Île-de-France recherche un titulaire de poste pour effectuer des études de chélation in vitro sur des isotopes dans des conditions simulant le tractus gastro-intestinal. Le candidat doit détenir un doctorat en chimie, posséder de solides compétences en chimie analytique et être capable de communiquer les résultats de recherche. Ce poste comprend la rédaction de publications scientifiques et la présentation lors de séminaires.
The position holder will carry out these in vitro chelation studies on synthetic media mimicking different compartments of the gastrointestinal tract (stomach, small intestine, colon) by varying the pH (2; 4.5 and 8), in the presence or absence of cations (mimicking the alimentary bolus) that can interfere with the chelation of the target isotopes and under thermostated conditions (37°C), to get as close as possible to physiological conditions. The principle of the tests is based on the evaluation of the chelation rate of the isotopes as a function of the quantity of polymer by the mean of ultrafiltration experiments : after an incubation period of MEX-CD1 with the isotopes, the mixture is ultrafiltered through a semi-permeable membrane. Depending on the nature of the radiation and the activities used, the analysis of the isotopes in the different fractions (filtrate and concentrate) will be carried out by inductively coupled plasma mass spectrometry (ICP-MS), alpha or gamma spectrometry.
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Europe, France, Ile-de-France, Hauts-de-Seine
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