Hotel Receptionist jobs in United Kingdom
Clinical Trial Manager – DEN-HOST Trial
University of Oxford
Discover more opportunities than anywhere else. Find more jobs nowReception Manager
DoubleTree by Hilton London Angel Kings Cross
Connect with headhunters to apply for similar jobsClinical Trial Manager – DEN-HOST Trial
Job summary
A prestigious research university in the UK is seeking an experienced Clinical Trial Manager for a multi-country trial. You will lead trial setup, oversee ongoing delivery, and ensure compliance while managing a team. Ideal candidates will have a strong background in biomedical research and international clinical trials. The position is full time on a fixed-term contract until September 2027, offering a competitive salary.
Qualifications
- Substantial experience in international trial set-up and delivery.
- Strong knowledge of ethics applications, sponsor approvals, and governance frameworks.
- Experience managing multi-partner budgets.
Responsibilities
- Lead trial set-up activities and establish Regional Coordinating Centres.
- Drive ongoing trial delivery and serve as the primary operational contact.
- Monitor enrolment and ensure governance and compliance.
Skills
Education
Help us to deliver a landmark, multi-country trial to find safe, affordable treatments for dengue. We are seeking to appoint an experienced Clinical Trial Manager to support DEN-HOST, a large randomised adaptive phase 3 trial evaluating therapeutics for patients hospitalised with moderate or severe dengue. This post will be based at Big Data Institute, Li Ka Shing Centre for Health and Information Discovery, Old Road Campus, Headington, Oxford, OX3 7LF.
The trial aims to identify safe and affordable treatments that prevent disease progression in high-risk patients and improve outcomes for those with established severe disease, thereby reducing the burden on health systems in dengue-endemic regions. DEN-HOST will initially test three host-directed therapeutics. The trial aims to recruit up to 8,000 patients across 25 sites in Peru, Colombia, Brazil, Bangladesh, Indonesia, Malaysia, Cambodia, Thailand, Nepal and Vietnam, over a 5-year period. It will build on established networks including RECOVERY, ISARIC, PREPARE and OUCRU.
- Lead trial set-up activities, including the establishment of Regional Coordinating Centres (RCCs) and the development of governance and operational frameworks.
- Drive ongoing trial delivery and oversight once recruitment begins, serving as the primary operational contact for RCC leads.
- Monitor enrolment and trial conduct, coordinate protocol amendments, and ensure governance and regulatory compliance.
- Oversee trial documentation and provide leadership within the Central Coordinating Office, including line-management of a Clinical Trials Assistant.
- Foster efficient, collaborative working practices across all partners and regions.
- Degree in a biomedical or related subject, or other relevant qualification or proven experience in clinical research; substantial experience in international trial set-up and delivery.
- Strong knowledge of ethics applications, Sponsor approvals, Clinical Trial Agreements, due diligence, risk and governance frameworks.
- Experience managing multi-partner budgets and reporting.
- Excellent communication skills and the ability to work collaboratively across multi-disciplinary, multi-country teams.
- Prior experience in line-management.
This position is offered full time on a fixed term contract until 30 September 2027 and is funded by Wellcome. Interviews will be held on week commencing 17 November 2025.
* The salary benchmark is based on the target salaries of market leaders in their relevant sectors. It is intended to serve as a guide to help Premium Members assess open positions and to help in salary negotiations. The salary benchmark is not provided directly by the company, which could be significantly higher or lower.