Mannequin-Jobs in United States

Intitulé du poste : stage 6 mois – R&D modèles in vitro intestinaux

Job title : 6 months internship – R&D In Vitro intestinal models

Lieu : Vitry-sur-Seine

A partir de : (start date not specified)

En tant que stagiaire au sein de l’équipe In Vitro ADME, vous participerez à une étude comparative entre le modèle Caco-2 et des systèmes in vitro complexes émergents, afin d’évaluer leur capacité à prédire la perméabilité intestinale des médicaments et leur métabolisme de premier passage chez l’humain.

As a R&D ADME intern within the In Vitro ADME team, you’ll participate in a comparative study between the Caco-2 model and emerging complex in vitro systems, assessing their ability to predict human drug intestinal permeability and first-pass metabolism.

• Participate in cultivating various cellular models using Transwell inserts and a microphysiological system
• Take part in characterizing models by analyzing marker expression at the mRNA level and assessing barrier function through measurements such as transepithelial electrical resistance and Lucifer Yellow permeability
• Collaborate to measure apparent permeability and intestinal clearance of reference compounds
• Assist in integrating data to predict the fraction of drug absorbed and intestinal bioavailability
• Soft and technical skills: rigor, autonomy, strong interpersonal skills; basic understanding of ADME and drug pharmacokinetics

• Education: Master’s degree in pharmacy, pharmacology, biotechnology, or bioengineering (Bac+5)
• Languages: English intermediate
• Basic understanding of ADME and drug pharmacokinetics

• Attractive internship bonus
• Depending on location, access to company restaurant with Sanofi contribution
• Fast and efficient recruitment process; initial telephone interview followed by meeting with manager
• Launch your career with a company that invests in you and empowers you to reimagine what’s possible
• Build your future with access to the latest tools, digital innovation, and continuous learning that keep you ahead of the curve
• Grow in a purpose-driven company where your voice matters and your work helps improve millions of lives
• Thrive in inclusive, flexible workplaces that support your personal and professional well-being

Chez Sanofi, nous croyons dans l’égalité des chances, sans distinction de race, de couleur, d’ascendance, de religion, de sexe, d’origine, d’orientation sexuelle, d’âge, de citoyenneté, de statut marital, de handicap, d’identité de genre ou de tout autre critère protégé par la loi.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.