Post-doctoral fellow (m/f) in the Structural Biology group

ESRF; Grenoble; Sur place; EUR 35 000 - 55 000; Plein temps

Résumé du poste

An international research institute is seeking a Post-doctoral fellow to contribute to neurobiology research, specifically targeting mitochondrial bioenergetics and Alzheimer's pathogenesis. The position involves developing X-ray micro-tomography and working with external researchers. Candidates must hold a PhD in a relevant scientific field and have experience in molecular biology and imaging techniques. This position promises a competitive compensation package and relocation support.

Prestations

Competitive compensation and allowances

Financial support for relocation

Workplace designed to support quality of life

Opportunity to join an international team

Qualifications

• PhD in a relevant field is mandatory.
• Experience with molecular biology and biophysical methods is required.
• Solid background in mitochondrial research and neurobiology is essential.

Responsabilités

• Contribute to neurobiology research focusing on mitochondrial bioenergetics.
• Participate in the development of X-ray micro-tomography.
• Serve as a Local Contact for user research on the MX beamlines.

Connaissances

Molecular biology and biophysical methods

X-ray crystallography

X-ray/EM imaging

Mitochondrial research and neurobiology

Ability to interact with multi-disciplinary staff

Proficiency in English

Formation

PhD in biophysics, biology, chemistry or closely related science

Description du poste

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Post-doctoral fellow (m/f) in the Structural Biology group, Grenoble

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Client:

ESRF

Location:

Grenoble, France

Job Category:

Other

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EU work permit required:

Yes

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Job Reference:

3652ecf71cc9

Job Views:

4

Posted:

12.08.2025

Expiry Date:

26.09.2025

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Job Description:

You will play a key role in the Structural Biology and Neurobiology inhouse research, as well as in the development of X-ray micro-tomography and other group activities.

The ESRF provides access to state-of-the art facilities for diffraction, solution scattering and cryo-electron microscopy experiments in Structural Biology. A critical component of the daily operation and methodological advancement of the Structural Biology Group (SBG) is the Biology Laboratory (CIBB lab), which is equipped for cloning and large-scale protein expression in model organisms such as bacteria, yeast, and mammalian cells. In addition, as part of the ESRF's participation in the Partnership on Structural Biology (PSB), the lab benefits from an extensive portfolio of cell biology and biophysical platforms.

As a Post-Doctoral Research Fellow, your missions will include:

• Contribute to the SBG’s in-house research on neurobiology, particularly on mitochondrial bioenergetics and neurodegeneration, with an emphasis on Alzheimer’s pathogenesis. This work will leverage a multiscale, multimodal approach that uses the advanced capabilities of ESRF beamlines, including cryo-EM.
• Participate in the development of a new X‑ray micro-tomography setup established at the ID30B beamline.
• Serve as a Local Contact for external user research on the MX beamlines at the ESRF.

Expected profile

• PhD in biophysics, biology, chemistry or closely related science
• Experience with molecular biology and biophysical methods
• Strong background in X-ray crystallography and X-ray/EM imaging
• Background in mitochondrial research and neurobiology
• Ability to interact with multi-disciplinary staff and facility users
• Proficiency in English (working language at the ESRF)

Working conditions

The salary will be calculated on the basis of relevant qualifications and professional experience.

Do you recognize yourself in this description? Apply now for your next professional adventure!

What we offer:

• Join an innovative international research institute, with a workforce from 38 different countries
• Collaborate with global experts to advance science and address societal challenges
• Come and live in a vibrant city, in the heart of the Alps, and Europe's Green Capital 2022
• Enjoy a workplace designed to support your quality of life
• Benefit from ourcompetitive compensation and allowances package, including financial support for your relocation to Grenoble