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Job title: HCPC registered Clinical Scientist

Reports to: Head of Laboratory

Location: Based onsite at Manchester Science Park

Contract Type: Full-time, Permanent

Salary & Benefits: Competitive Salary + Benefits Package

About Yourgene Health:

Yourgene Health is a leading integrated technologies and services business, enabling the delivery of genomic medicine. The group works in partnership with global leaders in DNA technology to advance diagnostic science. Our mission to enable scientific advances to positively impact human health remains at the core of our focus. It drives and motivates us to develop class leading products and services to meet our customers' needs.

Yourgene primarily develops, manufactures, and commercialises simple and accurate molecular diagnostic solutions, for reproductive health, precision medicine and infectious diseases. We have a comprehensive offering of non-invasive prenatal tests (NIPT) NGS workflows that have been built with labs in mind, and clinical prenatal screening services. The IONA test was the pioneer, the first to market as an IVD product, changing the NIPT screening landscape back in 2015. Continuing to build on our expertise in cell-free DNA, our next generation size selection Ranger Technology uses machine vision for superior precision. With multiple platforms for a range of clinical and research cfDNA sample preparation applications including NIPT, liquid biopsy, gene synthesis and long fragment recovery.

In addition, we offer a portfolio of screening products in reproductive health, precision medicine and infectious disease including screening assays for cystic fibrosis and DPYD genotyping to prevent chemotoxicity.

Yourgene Genomic Services provides a range of genetic analysis services for our clinical, research and pharma customers to support partners with DNA extractions, biobanking, genotyping, arrays and sequencing workflows (WES and WGS). Yourgene Genomic Services offers a Non-Invasive Prenatal Testing (NIPT) Service, enabling clinics to run their own NIPT service for pregnant women with our prenatal screening tests and service laboratory based in Manchester.

Yourgene Health is part of the Novacyt group of companies and is headquartered in Manchester, UK with facilities in Singapore and Canada.

Our Culture:

Yourgene is a growing, vibrant and exciting place to work, we are looking for committed driven individuals to be part of our next growth journey. Our culture is described by our employee's as collegiate, friendly, professional, innovative, open and fast paced. We have many social and wellbeing initiatives run by our Nova Social and Charity Huddle that keep our sense of community and togetherness alive. At Yourgene we focus on putting values led programmes in place to ensure that we can attract, retain and develop our people. We want our people to have a career with Yourgene and we ensure that they are recognised and rewarded for their achievements and commitment, everyone plays a critical role in our growth journey.

Description of role:

We have an opportunity for a full-time and permanent HCPC registered Clinical Scientist to join our genomic services team based onsite at Manchester Science Park. As a clinical scientist you will lead a team of scientists delivering clinical molecular testing services including a Non-Invasive Prenatal Testing within a ISO15189, CQC accredited lab.

You will use your expertise as a clinical scientist to lead the delivery of NIPT service laboratory ensuring compliance with quality and regulatory requirements. You will lead the development of new clinical services, leading the implementation and validation of new tests, ensuring the delivery of high quality testing services. You will lead the troubleshooting of assays and techniques both existing and in development. To implement laboratory procedures for sample receipt, processing, IQC, analysis, checking, interpretation, preparation of reports (both standard and complex) and reporting of results.

You will supervise more junior members of the team and cultivate an open, continuous improvement culture in the lab. In partnership with others, to be responsible for the accuracy, timeliness and appropriateness of a variety of genetic testing, returning results to ordering clinicians and customers.

Key areas of responsibility:

• To run clinical genetic testing service providing NIPT and other complex genetic tests.
• To supervise junior staff ensuring they are trained and maintain their competence in laboratory methods used to provide clinical tests.
• To develop and implement lab procedures to receive, track and process clinical samples.
• To provide expertise in the clinical interpretation of test results and communication of test results to clinicians.
• To use your expertise as a clinical scientist to assist other departments with the development of leading products and services in precision medicine and reproductive health.
• Conduct all activities in accordance with ISO 15189 and CQC requirements, following our quality management services and promoting a continuous improvement mindset.
• Maintain patient data integrity and regulatory compliance for all projects and documentation, adhering to GDPR, GCLP and HTA regulations.
• Identify and address non-conformities, deviations, and risks associated with laboratory activities.
• Develop study plans/protocols, SOPs, and technical documents, ensuring compliance and approval.
• Stand up new clinical services in accordance with the ISO15189 standards ensuring they assays are robust, verified/validated and offer our service customers state of the art molecular testing.
• Lead internal meetings, audits, and communication with senior management to ensure transparency and alignment.
• Liaise with the Quality Department to maintain correct documentation and SOPs.
• Coordinate service schedules with senior management and project managers to meet business needs.
• Ensure compliance with health and safety regulations, including COSHH systems.
• Stay updated on scientific advancements and industry trends to align with company strategy.

Qualifications, Skills and Abilities:

• BSc in an appropriate biological science
• State Registered Clinical Scientist
• 3+ years' experience working in a clinical laboratory carrying out molecular genetics testing
• Extensive experience working under ISO 15189 Quality Management System.
• Strong understanding of genetics, NGS, bioinformatics, diagnostics, and precision medicine.
• Experience in Oncology testing, whole genome sequencing and Reproductive Health is desirable.
• Ability to critically analyse and interpret scientific data.
• Ability to concentrate and work under pressure
• Excellent writing, oral communication, and presentation skills.
• Experience working with the selection of suitable bioinformatics and clinical reporting tools preferred.
• Demonstratable knowledge of patient consent, HTA, ethics and GDPR
• Confident communicator who is happy to communicate directly with external customers.
• Experience in the supervision of junior staff

Closing Date:

Sunday 10th August, 2025

Equal opportunities:

Yourgene Health and the Novacyt Group of companies provides equal employment opportunities for all current employees and applicants for employment. This policy means that no one will be discriminated against because of race, religion, creed, color, national origin, nationality, citizenship, ancestry, sex, age, marital status, physical or mental disability, affectional or sexual orientation, gender identity, military or veteran status, genetic predisposing characteristics or any other basis prohibited by law.

Notice to Agency and Search Firm Representatives:

Yourgene Health and the Novacyt Group of companies is not accepting unsolicited resumes from agencies and/or search firms for this job posting. Resumes submitted to any Yourgene Health and Novacyt Group employee by a third party agency and/or search firm without a valid written and signed search agreement, will become the sole property of Yourgene Health and the Novacyt Group of companies. No fee will be paid if a candidate is hired for this position as a result of an unsolicited agency or search firm referral. Thank you.