Clinical Trial jobs in United Kingdom

Applications are invited for a Clinical Research Fellow in the Ataxia Centre, UCL/UCLH Department of Neuroscience and Neurogenetics, UCL Institute of Neurology, under the supervision of Prof Paola Giunti. The post offers an exciting opportunity to gain experience of translational research as part of an internationally recognised multi‑disciplinary team.

The postholder will be an essential member of the research team at the Ataxia Centre, providing clinical and research input into the Centre's research programme into Ataxia and will work closely with the Principal Investigators, Clinical Research Fellows and Clinical Trials nurses. Their primary role will be as sub‑investigator in a clinical drug trial: a Phase 1/2a, open‑label trial to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending doses of intrathecally administered VO659 in participants with spinocerebellar ataxia types 1 and 3, assessing the safety of this novel antisense oligonucleotide (ASO) treatment in patients with these rare diseases.

He/she will also have the opportunity to participate in current basic and observational research, including longitudinal studies of dominant and recessive ataxias and at‑risk groups and healthy volunteers to identify reliable biomarkers of disease and develop new therapeutic targets.

• Medical degree and full GMC Registration
• Previous experience in neurology or general medicine
• Excellent skill in performing lumbar puncture
• Good interpersonal skills, ability to work cooperatively in a multidisciplinary setting
• Demonstrated record of academic clinical excellence

We offer permanent staff an interest‑free season ticket loan for travel, a subsidised social club including gym, a library for staff to use, free independent and confidential support for all staff, large retail discounts, car leasing scheme and on‑site accommodation.

Please note that if you have not heard from us within 3 weeks of the closing date of the advert you should assume that you have not been shortlisted on this occasion.

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services across eight sites:

• University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
• National Hospital for Neurology and Neurosurgery
• Royal National ENT and Eastman Dental Hospitals
• University College Hospital Grafton Way Building
• Royal London Hospital for Integrated Medicine
• University College Hospital Macmillan Cancer Centre

UCLH specialises in women's health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world‑class support services including critical care, imaging, nuclear medicine and pathology.