Clinical Research Fellow

University College London Hospitals NHS Foundation Trust; City of Westminster; On-site; GBP 80,000 - 100,000; Full time

Job summary

A leading NHS Trust is seeking a Clinical Research Fellow for the Ataxia Centre. The role involves providing clinical and research input into the Centre's research programme and being a sub-investigator in a clinical drug trial for ataxia treatments. Candidates should have a medical degree, GMC registration, and a strong background in neurology or general medicine. Benefits include a season ticket loan, subsidised social facilities, and additional perks. Join a dynamic multidisciplinary team committed to advancing ataxia research.

Benefits

Interest-free season ticket loan

Subsidised social club

Free independent support for staff

Large retail discounts

Car leasing scheme

On-site accommodation

Qualifications

• Medical degree and full GMC Registration required.
• Experience in neurology or general medicine is necessary.
• Must demonstrate excellent skill in performing lumbar puncture.
• Good interpersonal skills and ability to work in a multidisciplinary team.
• Proven academic clinical excellence needed.

Responsibilities

• Provide clinical and research input into Ataxia Centre's programme.
• Act as sub-investigator in a clinical drug trial.
• Participate in basic and observational research studies.

Skills

Medical degree and full GMC Registration

Experience in neurology or general medicine

Skill in performing lumbar puncture

Interpersonal skills

Record of academic clinical excellence

Job description

Clinical Research Fellow – Ataxia Centre

Applications are invited for a Clinical Research Fellow in the Ataxia Centre, UCL/UCLH Department of Neuroscience and Neurogenetics, UCL Institute of Neurology, under the supervision of Prof Paola Giunti. The post offers an exciting opportunity to gain experience of translational research as part of an internationally recognised multi‑disciplinary team.

The postholder will be an essential member of the research team at the Ataxia Centre, providing clinical and research input into the Centre's research programme into Ataxia and will work closely with the Principal Investigators, Clinical Research Fellows and Clinical Trials nurses. Their primary role will be as sub‑investigator in a clinical drug trial: a Phase 1/2a, open‑label trial to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending doses of intrathecally administered VO659 in participants with spinocerebellar ataxia types 1 and 3, assessing the safety of this novel antisense oligonucleotide (ASO) treatment in patients with these rare diseases.

He/she will also have the opportunity to participate in current basic and observational research, including longitudinal studies of dominant and recessive ataxias and at‑risk groups and healthy volunteers to identify reliable biomarkers of disease and develop new therapeutic targets.

Qualifications

• Medical degree and full GMC Registration
• Previous experience in neurology or general medicine
• Excellent skill in performing lumbar puncture
• Good interpersonal skills, ability to work cooperatively in a multidisciplinary setting
• Demonstrated record of academic clinical excellence

Benefits

We offer permanent staff an interest‑free season ticket loan for travel, a subsidised social club including gym, a library for staff to use, free independent and confidential support for all staff, large retail discounts, car leasing scheme and on‑site accommodation.

Please note that if you have not heard from us within 3 weeks of the closing date of the advert you should assume that you have not been shortlisted on this occasion.

About UCLH

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services across eight sites:

• University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
• National Hospital for Neurology and Neurosurgery
• Royal National ENT and Eastman Dental Hospitals
• University College Hospital Grafton Way Building
• Royal London Hospital for Integrated Medicine
• University College Hospital Macmillan Cancer Centre

UCLH specialises in women's health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world‑class support services including critical care, imaging, nuclear medicine and pathology.