Stage M2 : Characterization of the hemodynamics in the left atrium via 4DMRI

Société de Biomécanique; Saint-Étienne; Sur place; EUR 40 000 - 60 000; Plein temps

Résumé du poste

Un centre de recherche en ingénierie biomédicale à Saint-Étienne propose un stage de 6 mois en traitement d'images 4D pour la caractérisation des flux hémodynamiques dans l'oreillette gauche. Les candidats doivent avoir un Master en ingénierie biomédicale ou un domaine similaire, avec une curiosité pour les applications biomédicales. Le stage implique une collaboration avec des radiologues et le développement de méthodologies innovantes.

Qualifications

• Connaissance des méthodes de traitement d'images médicales.
• Intérêt pour les applications en biomécanique.
• Capacité à travailler en collaboration avec des radiologues.

Responsabilités

• Développer une méthodologie pour la caractérisation des flux intra-atriaux.
• Analyser les champs de vitesse et dériver des métriques spécifiques.
• Collaborer avec des radiologues pour le traitement d'images.

Connaissances

Traitement d'images

Traitement de signal

Mécanique des fluides

Applications biomédicales

Formation

Master en ingénierie biomédicale ou domaine similaire

Description du poste

Stage M2 : Characterization of the hemodynamics in the left atrium via 4DMRI

Master Internship position at the Center for Biomedical and Healthcare Engineering, Mines Saint-Etienne – Laboratoire SAINBIOSE INSERM UMR 1059 Characterization of the Hemodynamics in the Left Atrium via 4D Flow MRI Keywords: 4D flow MRI, Hemodynamics, Left Atrium

Overview

Academic context: The research group at Mines Saint-Etienne leads major international research projects in the domain of soft tissue and fluid biomechanics in the cardiovascular system through a longstanding collaboration with the University Hospital in Saint-Etienne. This internship is part of a larger collaborative project between Mines Saint-Etienne, the University Hospital of Saint-Etienne and the University of Washington, Seattle (ANR JCJC – Bacardyn).

Scientific context: The biomechanics of the Left Atrium (LA) represents an important gap in the understanding of different cardiovascular pathologies. Recently, atrial cardiomyopathy was defined as any electrical, structural and/or mechanical dysfunctions of the left atrium. Structural and electrical changes in the LA are interconnected and will directly impact the hemodynamics in the cavity. The major risk is that the modification of the hemodynamics in the LA results in thrombogenic flow patterns. The goal of the project is to understand how the modification in the structure of the LA wall impacts the hemodynamics in the LA. For this, the biomechanics of the LA, both from a structure and fluid point of view, will be characterized. The internship project will focus on one of these aspects: the hemodynamics in the left atrium. It aims at developing a methodology for the characterization of intra-atrial flow patterns from 4D flow MRI.

Project summary

Our group has previously developed methods to derive metrics from flow fields in cardiovascular applications. This project will start by developing an approach for the segmentation of the 4D flow MRI data, first starting with a static mask and then tracking the volume change across the cycle. Finally, the velocity fields will be analyzed and specific metrics will be derived to assess the left atrium function and potential thrombogenic risk. The work involves the combination of medical image processing and fluid mechanics. It will be performed in close collaboration with radiologists from the University Hospital of Saint-Etienne.

Student profile

Background in image processing, signal processing and/or fluid mechanics. Curiosity for biomedical applications.

Administrative aspects

This internship is funded for 6 months, starting in the first trimester of 2026. If you are interested, send a curriculum vitae and a short cover letter describing potential previous research experience and interests. Please, submit via email with “LA 4D MRI internship” on the subject line to Fanette Chassagne, PhD ([e-mail]).