Postdoc position in Mitochondrial Dysfunction in Aging and Diseases

Institute of Metabolic and Cardiovascular Diseases (Toulouse); France; Sur place; EUR 40 000 - 60 000; Plein temps

Résumé du poste

A research institute in Toulouse is seeking a Postdoctoral Fellow to investigate the relationship between mitochondrial functions and aging. The candidate will work on developing drug candidates and biomarkers related to mitochondrial dysfunction in the elderly. Applicants should have a PhD with a strong publication record, experience in aging biology, and proficiency in R. The role emphasizes independent work, communication skills, and teamwork in a supportive environment.

Qualifications

• Strong publication record.
• Good communication and teamwork skills.
• Ability to work independently with attention to detail.

Responsabilités

• Study the relation between mitochondrial functions and aging.
• Participate in the development of drug candidates and biomarkers.
• Contribute to a research community promoting personal and professional growth.

Connaissances

Experience in aging biology and/or mitochondrial metabolism

Interdisciplinary research experience

Proficiency in R

Formation

PhD

Description du poste

Institute of Metabolic and Cardiovascular Diseases (Toulouse)

Organisation/Company Institute of Metabolic and Cardiovascular Diseases (Toulouse) Research Field Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Established Researcher (R3) Application Deadline 14 Jan 2026 - 22:00 (UTC) Country France Type of Contract Temporary Job Status Full-time Offer Starting Date 1 Sep 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The project of the LiMitAging team (Lipoprotein and Mitochondrialadaptation inAging), led by Dr. Laurent Martinez, is to study the relation between some actors of mitochondrial functions and aging, and is driven by the hypothesis that enhancing mitochondrial health and mitochondrial quality‑control mechanisms will promote healthy aging.

The team's research in the field of lipoprotein and mitochondria led to identify original actors associated to lipid and mitochondrial energy metabolism.

Our objectives are to explore the physiological and pathophysiological roles of those molecular actors that regulate:

• The respiratory chain complex V, also called ATP synthase
• Autophagy, particularly mitophagy
• Ectopic ATP synthase and G protein‑coupled P2Y receptors signaling pathways

Team's work has led to the development of original drug candidates and biomarkers that are currently being validated on preclinical models and cohorts, for early detection and resolution of mitochondrial dysfunctions in pre‑frail elders or in population at high risk of cardiometabolic diseases.

The research topic's links to the research environment in Toulouse: The LiMitAging team participates in the large IHU HealthAge program on healthy aging, launched in 2024 (https://ihuhealthage.fr/en/). The IHU HealthAge consortium brings together the Gérontopôle of the Toulouse University Hospital and several research laboratories which have decided to combine their expertise to address key biological components (immunity, inflammation, metabolism, repair mechanisms) present in all organs, essential for their functioning and altered during aging.

Duration and specificity: 24 months. If selected, the applicant will apply to AToUT Programme (Attractiveness of Toulouse University for Transitions), postdoctoral fellowship initiative coordinated by the University of Toulouse and a core component of the TIRIS initiative (Toulouse Initiative for Research Impact on Society).

Experience

• Experience in aging biology and/or mitochondrial metabolism
• Experience with specific diseases or organ dysfunction
• Experience in interdisciplinary research, including the use of generative AI in medicine for dataset analysis
• Proficiency in R

Personal suitability, good communication and teamwork skills, inventiveness, and a proactive approach will be emphasized in the evaluation as well as relevant practical experience. The Postdoctoral Fellow will be expected to contribute to an active research community that promotes the personal and professional growth.

The position places great demands on the applicant’s capacity for independent goal‑oriented work, ability to concentrate and attention to detail.

In return, Dr. Martinez is committed to provide the training and resources needed for the lab members to achieve their goals at any point in their career path in an inclusive and inspirational environment.

Eligibility criteria

• PhD
• Strong publication record
• All nationalities
• Mandatory: Not have resided or worked in France >12 months in the 36 months before 28 February 2026

Additional Information

Work Location(s)

Number of offers available 1 Company/Institute Institute of Metabolic and Cardiovascular Diseases (Toulouse) Country France City Toulouse