Marie Sklodowska Curie Action - Postdoctoral individual Fellowship at IPBS-Toulouse, France (Ep[...]

euraxess.ec.europa.eu - Jobboard; France; Sur place; EUR 30 000 - 40 000; Plein temps

Résumé du poste

A leading research institute in France is seeking motivated postdoctoral researchers to join their laboratory and carry out innovative research on the role of citrullination in transcription control and cancer progression. Candidates should hold a PhD in Life Science and have published at least one first-author paper. This position offers a unique opportunity to work with state-of-the-art techniques in a vibrant international research community in Toulouse.

Prestations

Career development support

Mentoring for fellowship writing

Networking opportunities

Qualifications

• Candidates must hold a PhD in Life Science or have it before the application deadline.
• Published at least one first-author publication from his/her Ph.D.

Responsabilités

• Conduct research on the role of citrullination in transcription control and cancer progression.
• Apply multidisciplinary approaches in molecular biology and structural biology.

Connaissances

PhD in Life Science

Publication as first author

Description du poste

Organisation / Company Centre National de la Recherche Scientifique, Université de Toulouse Department Biology Laboratory Institute ofPharmacology and Structural Biology Is the Hosting related to staff position within a Research Infrastructure? No

The IPBS (Institute of Pharmacology and Structural Biology) is seeking motivated postdoctoral researchers to apply for Marie Skłodowska-Curie fellowships and join our laboratory to carry out their research project.

Research topic

Role of citrullination in transcription control and cancer progression.

Eukaryotic transcription regulation is functionally regulated by post-translational modification of chromatin. However, in this context, the function of one such modification, arginine citrullination, remains limited. Peptidyl arginine deiminases (PADIs) are a class of enzymes that catalyze the post-translational conversion of arginine to the non-coded amino acid citrulline. PADI2, a broadly expressed member of this family, plays a critical role in various cellular processes linked to tumor progression. Using state-of-the-art techniques, the lab is deciphering the molecular mechanisms by which PADIs-mediated citrullination coordinates with transcriptional events at multiple levels and dictates transcriptional plasticity and immune regulation in cancer. The prospective postdoctoral scientist will apply multidisciplinary approaches—including molecular biology, structural biology, cancer genomics, and patient-derived organoids, to elucidate the role of citrullination in tumor biology.

Keywords: Epigenetics, Citrullination, Inflammation, Immune hijacking, RNA Biology, Aggressive cancers, Transcriptional plasticity, Patient derived organoids

Experience/Skills required:

• Candidates must hold a PhD in Life Science or have it before the application deadline

Published at least one first-author publication from his/her Ph.D.

✅ Work at the cutting edge of molecular biology, structural biology, imaging, and omics technologies in Toulouse, France
✅ Join a vibrant international research community, with connections across Toulouse and throughout Europe
✅ Benefit from career development support, including mentoring for fellowship writing, networking, and future job applications

Application Process

• Send a detailed CV, a cover letter outlining your research interests and motivation for joining the group, and the contact information of at least 2 professional references (potential supporters and mentors) to:
• Internal deadline: 15 January 2026

Don’t hesitate to apply now as applications will be reviewed on a rolling basis.

• Expected Starting date: From September 2026 to September 2027 depending on the funding