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A*STAR’s Strategic Research and Translational Thrusts (SRTTs) are mission-focused programmes in strategic and emerging areas that are cross-disciplinary and of wider strategic interest to A*STAR and Singapore. Set up to address ambitious technological challenges towards impactful outcomes, each SRTT is led by a Programme Director (PD) and is centrally facilitated and supported by A*STAR HQ.

The Singapore Integrative Biosystems & Engineering Research (SIBER) SRTT harnesses synthetic biology capabilities to aid the sustainable transformation of Singapore’s Energy & Chemicals sector with the aim to expand to other sectors. It will create a synthetic biology platform initially for sustainable chemicals and fuels, powered by a unique organism library utilising the biodiversity of Singapore. SIBER’s vision is to be a premier hub in industrial biotechnology innovation for the energy / chemicals as well as other sectors, empowering Singapore to seize opportunities in the future bioeconomy.

We are looking for a Principal Investigator/Senior Principal Scientist/Senior Research Fellow with expertise in metabolic engineering to join our laboratory in A*STAR SIBER SRTT.

Job Description:

• Lead, design and perform experiments involving cutting-edge strain engineering and / or metabolic engineering harnessing synthetic biology and engineering biology approaches for the production of high-value chemicals in microbial cell factories. This also includes, for example, aspects of laboratory automation, protein biochemistry, cell-free systems, biosensing, biosynthesis pathway assembly.
• Develop applied research, translational and commercialisation strategies, in coordination with the SRTT leadership team.
• Work closely with the other SIBER SRTT team members as well as other relevant research institutes in A*STAR.
• Apply for individual research grants as part of career development and apply proactively for other research proposals.
• Present findings at seminars, meetings and national / international conferences.
• Write manuscripts for publication.
• Contribute to mentorship of PDRA, students, interns and technicians in the laboratory.
• Be an excellent communicator and team player.
• Build and maintain strong relationships with local and international research network

Requirements:

• PhD in Life Sciences, Biology, Biochemistry or a related field.
• At least more than 12 years of postdoc experience or independent research experience and leading a research team.
• Strong background in synthetic biology / engineering biology, molecular biology, biochemistry, chemical engineering, with a demonstrated capability for developing and implementing independent research activities at the cutting edge of the field.
• Track record of peer-reviewed scientific publications with at least five first-authored or last-authored papers in internationally recognised journals.
• Think methodically and have dedication, motivation, creativity and passion for scientific research and continuous learning.
• Exceptional analytical, experimental design, technical and problem-solving skills.
• Proficiency in communication by doing so in a straightforward and accurate manner, writing and editing scientific documents.
• Demonstrated ability to work independently as well as collaboratively and efficiently in an interdisciplinary team.
• Strong supervisory skills.
• A strong interest in the translational and applied aspects of research, including collaborations with industrial partners.
• Experience in omics technologies, HTP automation facilities, data analysis using various software, Design of Experiments and programming will be a plus.

We offer:

• A well-funded laboratory supported by A*STAR, the National Research Foundation (NRF) and industry to pursue a combination of exciting projects and your scientific interests.
• A nurturing, supportive and stimulating environment with close mentorship to develop your scientific career.
• Access to state-of-the-art technologies, scientific resources, core facilities and infrastructure housed within A*STAR to facilitate your research work.
• Access to collaborations with industrial partners to translate research findings to commercial applications and societal impact.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.