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The closing date is 21 December 2025

An exciting opportunity to work as a Clinical Research Nurse has arisen in the Cross Divisional Research Team. We are a team of experienced and dedicated professionals collaborating with our talented multi‑disciplinary clinical teams to deliver a wide range of innovative high quality research trials to inform the future care of our patients. The R & D team support a large and growing portfolio of studies across multiple specialities.

We offer a friendly working environment and are interested in your career development with a range of training opportunities available to help you fulfil your potential.

We are looking to appoint a Research Nurse who is enthusiastic, motivated, proactive and who will enjoy the challenge of delivering high quality research.

You will be based at the new Heart Lung Research Institute (HLRI) and Royal Papworth Hospital on the Cambridge Biomedical Campus.

As a key member of the Research Team, you will be responsible for the set up and coordination of multiple clinical trials. Your duties include recruiting and consenting suitable patients, coordinating data collection, arranging, and conducting assessments and follow‑up appointments which are specified by the protocol. All necessary tests and investigations will need to be arranged and appointment letters will need to be sent to patients to ensure that tests are performed at the scheduled times.

You will ensure that specified milestones are achieved on time, that high quality data is collected and that the trial is being conducted according to the ethically approved protocol and ICH‑GCP standards.

The post holder will be responsible for a portfolio of commercial clinical trials including randomised, controlled trials and observational studies.

Royal Papworth Hospital NHS Foundation Trust is the UK's leading heart and lung hospital, delivering care to more than 50,000 patients a year in its new state‑of‑the‑art hospital in Cambridge. We perform the most heart and/or lung transplants in the UK and carried out the UK's first successful heart transplant in 1979. It also offers emergency heart attack treatment, sleep centre care and is one of just five centres nationally for those in severe respiratory failure.

Based on the Cambridge Biomedical Campus the largest centre of medical research and health science in Europe the Trust is at the heart of treatments of the future. Royal Papworth became the first hospital trust in the country to be rated outstanding in all five areas assessed by the Care Quality Commission – a rating it still holds today. The Trust holds its values of compassion, excellence & collaboration at its core, and all colleagues joining the team are expected to uphold these in their day‑to‑day roles & interactions. Royal Papworth is proud of its diverse workforce and encourages people to embrace their individuality.

The Trust values difference and welcomes all applications irrespective of age, disability, gender reassignment, marriage and civil partnership, pregnancy & maternity, race, religion & belief, sex and sexual orientation. Providing they meet the minimum post criteria, applicants with disabilities will be offered an interview.

On this page you will find a Role Profile which provides information about the hospital and full details about the role. We recommend that you review this and refer to it as you complete your application. Please include how you will meet the Trust Values Compassion, Excellence and Collaboration. If you would like more information about the role or working at Royal Papworth Hospital, please get in touch with the contact for this role.

• Professional adult nursing or equivalent level science qualification; and clinical knowledge acquired through training to degree level OR diploma level qualification or above.
• Registered with Nursing and Midwifery Council or other regulatory body as applicable and / or NIHR CRP accreditation.

• To support the collection of clinical trial information and research samples in line with research legislation, adhering to procedures to ensure that confidentiality, accuracy, and security is maintained at all times and ensuring data collected meets required criteria.
• To conduct clinical assessments as per protocol within scope of practice and actively support the conduct of research trial(s) according to agreed research governance standards and legislation.
• To liaise with investigators, research delivery staff, research and development department, clinical departments and staff across RPH in respect of the study feasibility, set up and delivery and monitors the progress of that research study.
• To be able to demonstrate use of a range of judgement and assessment skills in planning, delivering and evaluating complex patient care plans as per trial protocol whilst communicating with patients, families and the multi‑disciplinary team. The post holder will be expected to manage routine studies but will be supported by their senior colleagues.
• To support complex patients with their potentially unpredictable care/treatment needs whilst participating in a clinical trial; ensuring care delivered is evidence based.
• The post holder will provide clinical services by undertaking diagnostic and research tests on patients for research purposes.
• The post holder will provide, implement and evaluate clinical knowledge and expert advice to the patient on the research study including any research treatment that needs to be considered alongside their substantive care plan.
• To be able to prioritise care based upon patient safety trial information need in a busy clinical environment and effectively prioritise own workload in line with local and regional targets and clinical trial visits in accordance with protocol‑mandated timelines and existing clinical appointments, escalating as necessary.
• To be able to undertake occasional moving and handling tasks relating to patient care utilising mechanical aids with some tasks requiring moderate effort.
• The post holder will have occasional exposure to some emotional / distressing incidents and frequent exposure to bodily fluids including from research sample collections, processing and shipping.
• To be able to effectively communicate complex, confidential, and/or sensitive condition related information through a range of interpersonal skills to colleagues, patients/visitors and external organisations (eg trial sponsors) (such as providing educational support, complex research planning); and to support patients to be able to make informed choices about health and treatment options related to clinical research trials.
• To act as a patient advocate when necessary, safeguarding and promoting the interests of patients and carers. This may involve explaining research procedures and the nature of the patient’s medical condition, in conjunction with the specialist clinical team, to ensure full understanding.
• To provide accurate and appropriate support for patients in conjunction with clinical nurse specialists and senior research colleagues.
• To work effectively within the research and development and clinical teams, maintaining professional relationships and good communication by participating in multi‑disciplinary research team meetings.
• To act in a professional manner and as a role model to other staff members, providing day to day clinical supervision of junior staff as well as patients and their families/carers.
• To understand the process of escalation within the trust ensuring this is done promptly to ensure patient and staff safety and recognising and raising any safeguarding concerns; including escalation to senior colleagues/investigator/ sponsors (as appropriate) under ICH GCP guidelines regarding adverse event documentation and reporting.
• To uphold Trust policies and procedures, knowing when to appropriately elevate and to act independently within own regulatory body Code of Conduct as appropriate.
• To be responsible for the day‑to‑day supervision of trial back up staff within their teams including allocating patient research activities.
• To support with the orientation of new staff, mentor new junior staff as appropriate (including research interns and student nurse placements); and support on‑going staff development.
• The postholder will take responsibility for own continuing professional development and ensure own knowledge remains current and is evidence based; and keeps abreast of current research and government issues relating to research and disseminate information as appropriate.
• To participate in reviewing policies and procedures to improve outcomes and the quality of service provided and actively participate in the implementation of any changes in practice within the clinical area, in line with statutory and NHS guidelines; and ensure timely dissemination of any agreed changes in practice.
• To support senior research colleagues with regular verbal and comprehensive written reports to the study investigators/study sponsors.
• To support senior research staff/line manager with monitoring/assessing and reporting in relation to both clinical and non‑clinical risks and incidents.
• To maintain accurate database entry/record keeping that is consistent with all legislation, policies, and procedures and , with the support of senior research colleagues, to anticipate, problems and issues on available data and identify and implement solutions.

• As well as being able to demonstrate examples of how they work in a way that is consistent with our values of compassion, excellence and collaboration the post holder will be able to clearly demonstrate a commitment to driving culture change through equality, diversity and inclusion.

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Royal Papworth Hospital NHS Foundation Trust