Clinical Research jobs in United States

Go back Guy's and St Thomas' NHS Foundation Trust

The closing date is 10 August 2025

This is an exciting opportunity to join a dynamic team with an international reputation for looking after children with rare genetic diseases.

Focussed on developing new therapies for disorders of the skeleton, we run ground-breaking clinical trials using precision medications. We are proud to adopt holistic care for our patients, advocating for the children and their families too, helping them navigate this complex and innovative research space in improving their medical care outcomes.

This is an unrivalled chance to learn new skills in a unique medical field, practise high-quality nursing and be part of an energetic team, dedicated to helping infants and young people with rare diseases.

As a Children's Research Nurse, you will play a key role in coordinating and delivering a genetic portfolio of research studies including. This expanding portfolio, consists of a number of observational, phase 2 and phase 3 clinical trials involving investigational medicinal product studies (CTIMPs). You will be responsible for the holistic nursing care of children / young people and their families on existing and new clinical trials and contribute to the assessment and management of care pathways for patients participating in clinical studies.

As a skilled communicator, the successful candidate, must also possess excellent interpersonal and problem-solving skills and be able to act as an ambassador for promoting research utilisation and best practice.

The normal working hours for the post is Monday - Friday 9am- 5pm although the post holder may need to be flexible to accommodate patient visits and assessments outside of these hours when required.

Guy's and St Thomas' NHS Foundation Trust comprises five of the UK's best known hospitals - Guy's, St Thomas', Evelina London Children's Hospital, Royal Brompton and Harefield - as well as community services in Lambeth and Southwark, all with a long history of high quality care, clinical excellence, research and innovation.

Dr Melita Irving has led the paediatric genetics team for several years, during which time she has helped establish whole exome sequencing as a diagnostic genetic test, and set up dedicated multidisciplinary clinics in skeletal dysplasia, achondroplasia-hypochondroplasia and dental genetics, including KBG syndrome. As a key opinion leader and expert in clinical trials in rare diseases of the skeleton, Melita holds a number of national and international positions of responsibility.

Our trials portfolio covers various commercial and non-commercial trials covering various skeletal dysplasia conditions and biologic treatments. We have a long tradition of clinical and scientific achievement and - as part of King's Health Partners - we are one of England's eight academic health sciences centres, bringing together world-class clinical services, teaching and research. We strive to recruit and retain the best staff as the dedication and skills of our employees lie at the heart of our organisation and ensure that our services are of the highest quality, safe and focused on our patients.

Comprehensive information is provided on the role and requirements within job description and person specification.

• Understanding of resource management, health and safety, clinical risk and quality issues
• Understanding of professional and current issues in children's nursing.
• Knowledge of clinical governance and improvement agenda
• Knowledge of research governance and regulations (ICH/GCP and EU Directives
• Knowledge of ethical and legal constraints of clinical research.
• Extensive experience of working within an acute paediatric ward environment as a qualified nurse with previous acute NHS experience
• Experience of handling clinical incidents and complaints
• Previous experience of research and audit
• Experience of staff management and development
• Venepuncture and cannulation trained

• NMC Registered Nurse (Child)
• Must be a holder of current paediatric immediate life support qualification
• Evidence of ongoing continuing professional development
• GCP accreditation

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Guy's and St Thomas' NHS Foundation Trust

£46,419 to £55,046 a yearp.a inc HCA (pro rata)