Research Technician

Cardiff University; Cardiff; On-site; GBP 33,000 - 37,000; Full time

Job summary

An esteemed university in Cardiff is hiring a Research Technician to support laboratory research in neuroinflammation and Alzheimer's disease. The role involves developing and testing novel complement-blocking drugs and investigating their impact on disease progression. This full-time position offers a salary range of £33,951 - £36,636 and excellent benefits including 45 days annual leave and a local pension scheme.

Benefits

45 days annual leave

Local pension scheme

Cycle to work scheme

Annual increments within the pay scale

Qualifications

• Experience in supporting similar laboratory research is encouraged.

Responsibilities

• Support a programme of laboratory research focusing on neuroinflammation and complement biology in Alzheimer's disease.
• Assist in the development and testing of brain-penetrant complement-blocking drugs.
• Investigate the impact of candidate drugs on disease pathology and progression.

Job description

Overview

Research Technician position in Neuroinflammation / Complement Biology at the UK Dementia Research Institute (UK DRI) - Cardiff University, School of Medicine, Heath Park campus.

This post joins a programme of research supported by the Moondance Foundation that explores the role of neuroinflammation in Alzheimer’s disease (AD). The work focuses on the roles of the complement system, a known driver of neuroinflammation and neurodegeneration, and the development and testing of novel brain-penetrant complement-blocking drugs in vitro and in vivo for their ability to inhibit the complement system, their penetrance into the brain, and their impact on disease pathology and disease progression. The ultimate aim is to develop brain-penetrant drugs to modulate complement dysregulation in AD that can be progressed to human trials.

Launched in 2017, the UK Dementia Research Institute (UK DRI) represents a major investment in dementia research with the goal of transforming the outlook for people living with or at risk of neurodegenerative conditions.

Responsibilities

• Support a programme of laboratory research focusing on neuroinflammation and complement biology in Alzheimer’s disease.
• Assist in the development and testing of brain-penetrant complement-blocking drugs, evaluating their ability to inhibit the complement system and penetrate the brain in vitro and in vivo.
• Investigate the impact of candidate drugs on disease pathology and progression, contributing to the goal of developing therapeutics suitable for advances to human trials.

Qualifications

• Experience in supporting similar laboratory research is encouraged to apply.

Details

Division: http://medicine.cf.ac.uk/infect-immun/

UK DRI Cardiff: https://ukdri.ac.uk/centres/cardiff

Post details: The post is full time (35 hours per week), available immediately and fixed term for one year.

Salary: £33,951 - £36,636 per annum (Grade 5). Appointments to roles at Cardiff University are usually made at bottom of scale unless in exceptional circumstances.

Benefits: Cardiff University offers many excellent benefits, including 45 days annual leave (incl bank holidays), local pension scheme, a cycle to work scheme, annual increments within the pay scale, and more. It is a Living Wage employer.

Important dates

Date advert posted: Wednesday, 24 September 2025

Closing date: Wednesday, 8 October 2025

Equality and inclusion

Cardiff University is committed to equality, diversity and inclusion. We welcome applicants from all backgrounds and acknowledge flexible working or job share arrangements where possible. Applications may be submitted in Welsh.

Cardiff University is a signatory to the San Francisco Declaration on Research Assessment (DORA). More information at: Responsible research assessment - Research - Cardiff University