Principal Statistician

QUANTICATE INTERNATIONAL LIMITED; Manchester; Hybrid; GBP 125,000 - 150,000; Full time

Job summary

A leading data-focused CRO is seeking a Principal Statistician in Manchester. You'll lead clinical trials, develop and validate statistical models, and mentor junior statisticians. The ideal candidate possesses a master's in Biostatistics and strong expertise in clinical methodologies and SAS programming. This role offers a competitive salary, flexible hours, and substantial career progression opportunities in a dynamic environment.

Benefits

Competitive Salary

Home working allowance

Flexible working hours

25 days Annual leave plus bank holidays

Pension with Company matching

Private medical Scheme with Bupa

Employee Assistance Program

Qualifications

• Strong statistical expertise with experience in clinical trials.
• Experience with Adaptive design/analysis and Bayesian Statistics.
• Extensive knowledge of regulatory requirements for clinical trials.

Responsibilities

• Serve as lead statistician for clinical trials, ensuring quality deliverables.
• Develop and validate statistical models and analyses based on protocols.
• Write statistical analysis plans and reports.

Skills

Statistical expertise

SAS programming

Project management

Communication skills

Education

MSc in Biostatistics, Medical Statistics or equivalent

Job description

Description

We are seeking an experienced Principal Statistician to join our growing team. The successful applicant will work as part of global teams, supporting pharmaceutical, biotechnology and medical device companies across many therapeutic areas. Quanticate values quality first, integrity, care, people, commitment to delivery, and inspiration. As such, employees are offered flexible and friendly working conditions, competitive pay, industry-leading benefits, and opportunities for progression, in an environment where they are mixing with the very best experts in the field.

As Principal Statistician, you will be responsible for the development, validation, and implementation of statistical models and providing statistical support for clinical studies. You will serve as a Statistical Lead for large-scale clinical trials across various therapeutic areas, ensuring that all deliverables are achieved on time and to a high level of quality. You will lead Statistical Consultancy Projects, advising clients on all aspects of statistical trial design and conduct. Key to the role is, the ability to provide face to face advice to clients on all elements of study design, whether frequentist or Bayesian in nature. Having experience of using simulation methods in trial design would be an advantage but not essential. Through all activities you will also provide guidance and mentorship to other statisticians in the group.

Responsibilities

• Serve as lead statistician for clinical trials including planning, analysing, and reporting, ensuring that all deliverables are met on time and to a high level of quality.
• Develop and validate statistical models and analyses based on study protocols.
• Write statistical analysis plans and reports.
• Provide guidance and mentorship to other statisticians in the group.
• Collaborate with cross-functional teams to develop study protocols and ensure they meet regulatory requirements.
• To potentially take line management responsibility for junior statisticians within the team.
• To lead statistical consultancy projects as required, providing expert statistical advice on all statistical aspects of study design and conduct.
• Perform ad hoc statistical duties as required

Quanticate is the world leading data-focused CRO, and we often work with our customers on their complicated clinical trials which require a high level of statistical programming, statistics and data management input. We need talented individuals to help us fulfil our customers’ needs.

Our customers range from top global pharmaceutical companies where you can work as an integrated team member on a world leading clinical program, to small biotechs that are taking their first steps in clinical development

We strongly advocate career development providing membership to professional societies, encouraging your involvement in their activities and committees. Together we can help you build the career you want – developing your skills, working on challenging problems, to ultimately develop clinical therapies that matter.

Requirements

• Essential - MSc in Biostatistics, Medical Statistics or equivalent.
• Strong statistical expertise with experience in clinical trials.
• Experience with Adaptive design / analysis and Bayesian Statistics.
• Experience in SAS programming.
• Extensive knowledge of regulatory requirements for clinical trials.
• Strong project management and leadership skills with experience leading large-scale projects.
• Excellent verbal and written communication skills.
• Ability to work independently and as part of a team.
• Willingness to travel when needed.

Benefits

• Competitive Salary (Open to discussion based on experience)
• Home working allowance
• Flexible working hours
• 25 days Annual leave plus bank holidays
• Option to purchase additional days holiday
• Pension with Company matching
• Private medical Scheme with Bupa
• Free standard eye test every two years
• Employee Assistance Program – Available for employee and immediate family
• 5, 10, 15 years of service recognition awards
• Death in service scheme
• Long Term Disability Insurance
• Quanticate offers a variety of different learning development opportunities to help you progress (mentoring, coaching, e-learning, job shadowing)