Lentiviral Process Dev Scientist I - London Lab

Orchard Therapeutics; Greater London; On-site; GBP 30,000 - 45,000; Full time

Job summary

A biotechnology company in Greater London is seeking a Scientist I to perform laboratory-based activities supporting lentiviral vector process development. The role includes executing upstream and downstream process studies, performing vector analytics, and generating technical documentation while collaborating with cross-functional teams to support development and regulatory requirements. Ideal candidates should have 2-5 years of experience in biotechnology, especially in cell and gene therapy. A BSc, MSc, or PhD in relevant fields is required.

Qualifications

• Approximately 2 to 5 years’ experience in biotechnology/biological sciences with focus on cell and gene therapy.
• Experience in Upstream Process (USP) operations for vector production.
• Understanding of regulatory filings and associated reports/sections writing.
• Hands-on experience with suspension bioreactors and DSP processes.
• Familiarity with FDA, EMA, GMP, and ICH regulatory requirements.

Responsibilities

• Perform laboratory activities for lentiviral vector (LVV) manufacturing processes.
• Design and execute experiments with guidance, including data analysis.
• Collaborate with cross-functional teams to meet project timelines.
• Author and review development protocols and technical reports.
• Contribute to vector laboratory upkeep and ensure safety standards.

Skills

Excellent interpersonal skills

Positive can-do attitude

Outstanding organizational skills

Excellent written and oral communication skills

Creative problem solver

Experience authoring development reports

Education

BSc, MSc or PhD in bioprocessing, biological sciences, gene therapy or related subject

Job description

A biotechnology company in Greater London is seeking a Scientist I to perform laboratory-based activities supporting lentiviral vector process development. The role includes executing upstream and downstream process studies, performing vector analytics, and generating technical documentation while collaborating with cross-functional teams to support development and regulatory requirements. Ideal candidates should have 2-5 years of experience in biotechnology, especially in cell and gene therapy. A BSc, MSc, or PhD in relevant fields is required.