Higher Scientific Officer (bioinformatician)

The Institute Of Cancer Research; London; On-site; GBP 35,000 - 50,000; Full time

Job summary

A leading cancer research institute in London seeks a Bioinformatician (Senior Scientific Officer) to analyze RNAseq data and develop methodologies within a dynamic research environment. The role requires a Master's degree and experience in bioinformatics analysis and software development. Collaboration and a supportive atmosphere are guaranteed, alongside competitive salary and benefits.

Benefits

Dynamic research environment

Access to state-of-the-art facilities

Professional development opportunities

Competitive salary and pension

Qualifications

• Master's degree in Computational Biology, Bioinformatics, Computer Science, or related subject required.
• Proven bioinformatics analysis experience in NGS and clinical data analysis.
• Experience in software pipeline development for analytical workflows.

Responsibilities

• Conduct bioinformatics analyses and interpret RNAseq data.
• Develop methodologies for research activities.
• Present results to project teams and collaborators.

Skills

Bioinformatics analysis

NGS analysis (WES/WGS/RNAseq)

Software pipeline development

High Performance Computing experience

Python coding

R coding

Bash scripting

Git version control

Education

Master's degree in Computational Biology or related field

Job description

Key Information

Reporting to: Prof Anguraj Sadanandam

Duration of Contract: Fixed Term for 12 months

Hours per week: 35 hours per week (Full Time)

Location: Sutton

Closing Date: 30th September 2025

This role is eligible for ICR Sponsorship. Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here.

Job Details

Under the guidance of Prof Anguraj Sadanandam, we are seeking to recruit a Bioinformatician (Senior Scientific Officer) to contribute to implementing and performing relevant analyses, interpreting the results in context of fast-moving projects, and presenting the results to project teams as well as internal and external collaborators and contribute, with the expectation of authorship on resulting publications. There will also be opportunities to engage in bench-based experimental research, although this is not mandatory. The successful candidate will play a key role in analysing RNAseq data (bulk, single-cell, spatial), developing methodologies and supporting research activities.

About you

The successful candidate must have:

• Master's degree in Computational Biology, Bioinformatics, Computer Science, or related subject
• Proven experience of bioinformatics analyses and interpretation in one or more of the following key areas (NGS analysis of WES/WGS/RNAseq (bulk, single-cell) using standard practice pipelines; Clinical data analysis (Survival curves, correlation and subgroup analysis)
• Proven experience in the development of software pipelines to implement analysis workflow
• Proven experience in use of High Performance Computing platforms and unix-like operating systems
• Proven experience of writing and maintaining Python, R and Bash code using Git

Department/Directorate Information

The Division of Molecular Pathology conducts translational research linking molecular science to clinical oncology. The group of Dr Anguraj Sadanandam focuses on cancer metabolism and tumour subtypes, particularly in pancreatic ductal adenocarcinoma (PDAC) and colorectal cancer (CRC). Using integrative multi-omics approaches - including scRNAseq, spatial transcriptomics, bulk RNAseq, metabolomics (LC-MS), CNV, and WES - combined with cell culture and genetically engineered mouse models, we aim to define tumour heterogeneity and identify new therapeutic opportunities.

The successful candidate will work under multidisciplinary supervision: for clinical and biological questions, guidance will be provided by Dr Christophe Cisarovsky, Clinical Oncologist in the GI clinic at The Royal Marsden Hospital and MD-PhD, together with Group Leader Prof Anguraj Sadanandam; for technical and bioinformatics questions, supervision will be provided by Prof Anguraj Sadanandam and members of his bioinformatics team. The candidate will primarily perform bioinformatic analyses and contribute to fast-moving projects with the expectation of authorship on resulting publications. There will also be opportunities to engage in bench-based experimental research, although this is not mandatory.

https://www.icr.ac.uk/research-and-discoveries/find-a-researcher/test-researcher-profile-detail/dr-anguraj-sadanandam

What we offer

• A dynamic and supportive research environment
• Access to state-of-the-art facilities and professional development opportunities
• Collaboration with leading researchers in the field
• Competitive salary and pension

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Christophe Cisarovsky via Email on [email protected].

About The Institute of Cancer Research

Why work for us?

As a member of staff, you'll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.

At the Institute of Cancer Research, we champion diversity as we believe it fuels innovation and drives impactful research. We welcome applicants from all walks of life, valuing diverse perspectives that enrich our work.

Don't let a checklist of qualifications hold you back - if you're passionate about the role, we want to hear from you. Your unique experiences and backgrounds contribute to the richness of our team. We are committed to being an equal opportunity for all, regardless of ethnicity, gender, age, sexual orientation, disability, or any other dimension of diversity. Join us in creating an inclusive environment where everyone's voice is heard and valued.