{"@context":"https:/schema.org/","@type":"JobPosting","title":"Senior Scientist - In Vitro Biology

Discovery Inc; Portishead; On-site; GBP 45,000 - 65,000; Full time

Job summary

A leading biopharmaceutical company in Portishead, England is seeking a Senior Scientist to lead immunological assays in a lab-based environment. The ideal candidate will have an MSc or PhD in Immunology and strong experience in immuno-oncology. This role offers an excellent benefits package and the opportunity to contribute significantly to drug discovery efforts.

Benefits

Generous pension contribution

Flexible health benefits

CREDS discounts

Qualifications

• MSc in Immunology with industry experience or PhD in Immunology desirable.
• Expertise in B and T cell immunology.
• Demonstrable lab-based experience in immuno-oncology, autoimmune disease and inflammation.
• Awareness of Health and Safety standards within the labs.
• Excellent communication skills.
• Strong passion for drug discovery.
• Strong problem-solving and collaboration skills.

Responsibilities

• Independently run a wide range of immunological assays.
• Implement and develop new immunological assays.
• Interrogate data to generate scientifically sound reports.
• Guide, coach and mentor junior scientific staff.
• Lead IVB studies or execute studies with minimal supervision.
• Collaborate with BD/CS on novel work introductions.

Skills

Immunology

Lab-based experience in immuno-oncology

Strong communication skills

Problem-solving skills

Collaboration skills

Proficient in IT (Microsoft, Outlook, Teams)

Education

MSc or PhD in Immunology

Job description

Overview

Senior Scientist opportunity at our Waterside site in Portishead, Bristol. You will work independently under strategic guidance with understanding and application of scientific and technical standards in a predominantly lab-based in vitro biology environment.

Responsibilities

• Independently run a wide range of immunological assays using techniques such as flow cytometry, IncuCyte, MACS sorting, culture and differentiation of primary cells and cell lines, ELISA, Luminex, TR-FRET, and ex-vivo tissue processing.
• Implement available assays and develop new immunological assays to support in vitro biology capabilities in immuno-oncology, autoimmune disease and inflammation (including neuroinflammation), infection or microbiome programs.
• Interrogate data to generate reports where conclusions and future directions are scientifically sound; provide technical and scientific leadership to drive project progression.
• Guide, coach and mentor junior scientific staff, training on specific techniques and sharing technical knowledge as needed.
• Project lead or deputy project lead for IVB studies, or execute studies with minimal supervision from the project lead.
• Leverage BD/CS and operational teams to introduce novel work for the site, including scoping calls with clients and revising scientific project proposals.

Qualifications

• MSc in Immunology with industry experience or PhD in Immunology desirable.
• Expertise in B and T cell immunology.
• Demonstrable lab-based experience in immuno-oncology, autoimmune disease and inflammation (including neuroinflammation).
• Awareness of Health and Safety standards within the labs and ability to work safely in this environment.
• Excellent communication skills, able to relay scientific information accurately.
• Strong passion for drug discovery, able to stay abreast of industry updates and share with peers.
• Strong problem-solving and collaboration skills; proficient in IT (Microsoft, Outlook, Teams).
• Clear understanding of the drug discovery process.
• Nice to have: previous industry lab experience (pharma/CRO/biotech); project leadership experience; experience working in a multidisciplinary unit on integrated drug discovery projects; demonstrable skills in executing biological assays in a pharma/biotech/CRO environment.

About Discovery and Benefits

Discovery from Charles River is industry-proven in the successful development of novel therapies and provides chemistry, biology, and pharmacology services to support clients from hit identification through IND. We offer a comprehensive benefits package from day one, including a generous pension contribution, flexible health benefits, and CREDS discounts. We are committed to diversity and inclusion and support global opportunities and career progression.