Biotechnologie à France

Inserm 1037 - Cancer Research Center of Toulouse - University of Toulouse III

Organisation/Company Inserm 1037 - Cancer Research Center of Toulouse - University of Toulouse III Department Immunology Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions Postdoc Positions Country France Application Deadline 4 Dec 2025 - 12:00 (Europe/Paris) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 5 Jan 2025 Is the job funded through the EU Research Framework Programme? Horizon Europe - ERC Reference Number Syn- 951329 Is the Job related to staff position within a Research Infrastructure? No

A post-doctoral research position funded by a prestigious European Research Council Synergy Grant is available immediately in the team of Dr. Salvatore Valitutti at the Cancer Research Center (CRCT) of Toulouse, France. The research is based on a dynamic international collaboration with the University of Oxford (UK), the University of Siena (Italy) and the University of Saarland (Germany). The specific aim of the project is to define the molecular mechanisms of tumor cell resistance to cytotoxic T lymphocyte (CTL) attack at the immunological synapse and to dissect their cell death pathways with the purpose of enhancing CTL efficacy in tumor eradication and improving the efficacy of immunotherapies in cancer patients (Balint et al. Science 2020; Filali et al. Science Advances 2022; McKenzie et al. Trends in Cancer 2023). The research will be performed on clinically relevant samples using latestgeneration imaging techniques. The ideal candidate for this position has a strong background in immunology and/or cell biology and is interested in studies related to molecular mechanisms of cytotoxicity at the immunological synapse. Experience with molecular biology methods is desirable as well as excellent capabilities with human primary cell culture and/or strong expertise in imaging techniques. As the successful applicant will be part of a highly collaborative international team, strong interpersonal skills and English fluency are considered assets. The CRCT is a newly built INSERM, CNRS, Toulouse University research center which specializes in multidisciplinary translational research including oncology, hematology, and immunology. The center is located in a modern biotechnology campus and is adjacent to the Clinical Cancer Center of Toulouse (IUCT Oncopole) allowing CRCT scientists to work in close cooperation with clinicians. The CRCT hosts 18 highly successful research teams and eight core facilities grouped within a Technology Center (website: https://www.crct-inserm.fr/en/).

The applicant should have a PhD in immunology or cell biology or biophysics and a solid publication record.

The ideal candidate for this position has a strong background in immunology and/or cell biology and is interested in studies related to molecular mechanisms of cytotoxicity at the immunological synapse. Experience with molecular biology methods is desirable as well as excellent capabilities with human primary cell culture and/or strong expertise in imaging techniques.

Specific Requirements

As the successful applicant will be part of a highly collaborative international team, strong interpersonal skills and English fluency are considered assets.