Biotechnologie jobs in United States

• Isolate, amplify, characterize primary human cells (immunofluorescence, RT-qPCR, clonogenicity, scRNA-seq, ATAC-seq)
• Participate in multi-omics analyses (scRNA-seq, ATAC-seq)
• Establish cell reprogramming protocols
• Functional evaluation of reprogrammed cells in vitro and in vivo
• Co-supervision of Master's 2 students
• Contribute to scientific publications, patent filings, and oral presentations
• Participate in project meetings and team dynamics

Geographic mobility: No business trip. Telework, occasional.

• PhD in cell biology / biotechnology
• Solid experience in cell culture (primary cells, differentiation, transduction / transfection, possibly iPSCs)
• Good knowledge of molecular biology, histology, and microscopy
• Knowledge and experience in scRNA-seq, ATAC-seq, and bioinformatics analysis are a plus
• Ability to work independently while interacting in a multidisciplinary team. Scientific rigor, motivation, creativity, initiative, and a desire to develop projects. Good communication and organizational skills.
• Scientific English essential; French is not mandatory
• A minimum of one publication as first author required

The Recor project lies at the crossroads of cell biology and computer science, aiming to open up a new avenue for the manufacture of cell therapy products. The project aims to develop a treatment for limbal stem cell deficiency (LSCD) by generating corneal epithelial stem cells from adult somatic cells by direct cellular reprogramming. With our partner, we will integrate multi-omics data (scRNA-seq, ATAC-seq) using bioinformatics tools to define optimal reprogramming conditions, then confirm them through phenotypic characterization and in-vivo functional validation. This regenerative medicine program, funded by the French National Research Agency (ANR) and conducted in international collaboration, is designed to provide the preclinical evidence necessary for clinical translation in humans.