Postdoctoral Position – Functional Genomics of Lymphoma

CIML2000; France; Sur place; EUR 35 000 - 45 000; Plein temps

Résumé du poste

A research organization in France is seeking a postdoctoral researcher to join a team focusing on genomic and transcriptomic studies related to human lymphomas. The candidate will work on generating and analyzing data using CRISPR and single-cell models, validate targets, and contribute to scientific publications. A PhD in Immunology or Oncology and strong experience in CRISPR screening and bioinformatics are essential for this full-time position. The starting date is January 2026.

Qualifications

• Strong experience in CRISPR screening and bioinformatic analysis integrating CRISPR and single-cell data.
• Proficiency in genetic perturbation methods using CRISPR in vitro and in vivo.
• Ability to maintain scientific and methodological awareness relevant to the research theme.

Responsabilités

• Generate functional genomics data (CRISPR and single-cell) using human lymphoma patient-derived models.
• Perform and finalize the analysis of CRISPR screening experiments.
• Validate identified targets through CRISPR-based perturbation assays.

Connaissances

CRISPR screening

Bioinformatic analysis

Proteomic analyses

Communication skills

Formation

PhD in Immunology or Oncology

Outils

Mass spectrometry

Flow cytometry

Description du poste

Organisation/Company CIML2000 Research Field Biological sciences » Biology Medical sciences » Cancer research Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Country France Application Deadline 31 Jan 2026 - 13:00 (Europe/Paris) Type of Contract Temporary Job Status Full-time Hours Per Week 38 Offer Starting Date 5 Jan 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The postdoctoral researcher will join Sandrine Roulland’s team at the Centre d’Immunologie de Marseille-Luminy (CIML). The group investigates genomic and transcriptomic deregulations involved in the development and progression of human lymphomas.

The successful candidate will contribute to a research program aimed at generating, interpreting, and validating large‑scale genomic data to dissect and model the cellular heterogeneity of follicular lymphomas, characterize their oncogenic dependencies, and functionally validate them using CRISPR‑based genetic perturbation approaches.

Through integrative analyses, the team also seeks to decipher the biological mechanisms underlying relapse and therapeutic resistance. The researcher will actively contribute to data analysis, synthesis of results, and preparation of scientific publications related to the project.

The postdoc will work in close collaboration with a network of bioinformaticians specializing in the design and development of data analysis pipelines for functional genomics, including CRISPR and single‑cell approaches.

Responsibilities

Generate functional genomics data (CRISPR and single‑cell) using human lymphoma patient‑derived models.

Perform and finalize the analysis of CRISPR screening experiments and generate graphical representations of results.

Validate and consolidate identified targets through CRISPR‑based perturbation assays, combined with transcriptomic and proteomic analyses in both human and murine models.

Evaluate therapeutic combinations using drug screening assays (viability tests, MTS assays, etc.).

Analyze, interpret, and communicate research findings with collaborators and contribute to scientific publications (manuscript writing, figure preparation).

Required skills and qualifications

Strong experience in CRISPR screening and bioinformatic analysis integrating CRISPR and single‑cell data.

Where to apply

E-mail [e-mail]

Requirements

Research Field Biological sciences » Biology Education Level PhD or equivalent

Skills/Qualifications

Strong experience in CRISPR screening and bioinformatic analysis integrating CRISPR and single‑cell data.

Proficiency in genetic perturbation methods using CRISPR in vitro and in vivo.

Experience with proteomic analyses by mass spectrometry and flow cytometry.

Ability to maintain scientific and methodological awareness relevant to the research theme.

Demonstrated autonomy, initiative, organizational skills, scientific rigor, adaptability, and enthusiasm.

Excellent communication skills for interdisciplinary collaboration with biologists and bioinformaticians.

Proven ability to draft scientific reports, manuscripts, and figures in English.

Fluency in written and spoken scientific English.

Specific Requirements

PhD in Immunology or Oncology

Strong interdisciplinary interactions with both the biology research team and the CIML bioinformatics/statistics platform.