Engineer in biology (F/M)

Institut Curie; Paris; Sur place; EUR 40 000 - 60 000; Plein temps

Résumé du poste

A prestigious cancer research institute located in Paris seeks an Assistant Engineer to contribute to a project involving DNA repair studies in mammalian cells. Responsibilities include maintaining cell lines, performing electroporation experiments, and analyzing outcomes. The ideal candidate will have a Bachelor or Master’s degree in a relevant field and 2-3 years of experience with mammalian cell culture, particularly in CRISPR techniques. Full-time fixed-term contract with competitive remuneration and benefits, starting January 2026.

Prestations

Collective catering

Transportation fee reimbursement up to 70%

Supplementary health insurance

Qualifications

• At least 2-3 years of hands-on experience in mammalian cell culture.
• Experience with CRISPR editing is strongly recommended.
• Solid background in cellular and molecular biology techniques.

Responsabilités

• Maintain several cell lines.
• Perform electroporation experiments and molecular assays.
• Analyze experiments using imaging and molecular biology techniques.
• Collaborate with researchers to analyze data.

Connaissances

Organizational skills

Teamwork

Fluency in English

Formation

Bachelor or Master’s degree in molecular and cellular biology or related field

Outils

PCR

RT-qPCR

Library preparation

Description du poste

About Us

The “Institut Curie” is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness.

The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

Laboratory

Institut Curie, CNRS UMR 3244 – team Valérie Borde: Chromosome Dynamics and Recombination

https://institut-curie.org/team/borde

Missions

Our team Chromosome Dynamics and Recombination investigates the mechanisms that repair programmed and accidental DNA double-strand breaks (DSB) in order to maintain genome stability and that are often disregulated in cancers. We combine yeast genetics, mammalian cell culture, proteomic and genomic approaches to decipher the fine molecular mechanisms of homologous recombination during meiosis or somatic growth.

Our team is seeking a motivated Assistant Engineer (AI) or Study Engineer (IE) in Biology to contribute to a project investigating the study of DSB repair in mammalian cells by advanced genome sequencing, using an innovative way to target DSB at specific sites. For this, the recruited IE will develop the novel CRISPR editing approach that we intend to use in different wildtype and mutant backgrounds.

The Successful Candidate Will Be Responsible For

• Maintenance of several cell lines.
• Performing electroporation experiments and molecular assays (including CRISPR technology) to induce double-strand breaks.
• Analyze the outcome of these experiments by imaging and molecular biology such as ChIPseq assays and library preparation. Bioinformatic analyses will be performed with a researcher in the lab.
• Collaborating closely with researchers to analyze experimental data and contribute to the advancement of the project.

Candidate Profile

• Education: Bachelor or Master’s degree (MSc) in molecular and cellular biology, biotechnology, or a related field.
• Experience: At least 2-3 years of hands‑on experience in mammalian cell culture (mandatory). Experience with CRISPR editing is strongly recommended.
• Solid background in cellular and molecular biology techniques (PCR, RT-qPCR, library preparation…)

Skills Required

• Good organizational skills, ability to work both independently and in a team.
• Rigor, motivation, and enthusiasm for research.
• Fluency in English.

Contract information

Type of contract: Fixed‑term contract

Starting date: 15/01/2026

Duration: 5 months

Working time: full time

Remuneration: according to qualification and the current grids

Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance

Location of the position: Paris

Contact

Please send your CV, letter of motivation and 2 references

Publication date: 09/12/2025

Deadline for application: until filled

Equal Opportunity Statement

Institut Curie is an inclusive, equal opportunity employer and is dedicated to the highest standards of research integrity.

https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf

Référence de l'offre : o4m1valuvm