Research Scientist (Lead Optimisation Unit)

CHUGAI PHARMABODY RESEARCH PTE. LTD.; Singapore; On-site; SGD 70,000 - 100,000; Full time

Job summary

A biopharmaceutical company in Singapore is looking for a Senior Scientist in the Lead Optimization Unit. The ideal candidate will possess a Ph.D. in a relevant field and have proven expertise in structural biology and molecular biology, as well as protein engineering. Strong collaboration skills and command of Japanese and English are required for effective communication with teams in Singapore and Japan. Interested applicants should email their resume and salary expectations.

Qualifications

• Strong and proven expertise in structural biology and molecular biology.
• Advanced knowledge in protein and/or antibody engineering.
• Expertise in protein biochemistry, expression, purification, and characterization.

Responsibilities

• Conduct protein structure/function investigations.
• Demonstrate technical expertise in molecular biology and cell biology.
• Collaborate with cross-functional multi-disciplinary teams.

Skills

Structural biology

Molecular biology

Protein engineering

Protein biochemistry

Team collaboration

High-throughput systems

Cell biology

Biophysics

Immunology

Education

Ph.D. degree in Biomedical Science/Biochemistry/Chemical Biology/Biotechnology/Information science

Job description

Chugai Pharmabody Research Pte. Ltd. ("CPR") was established in Singapore as a wholly‑owned subsidiary of Chugai Pharmaceutical Co., Ltd (Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Biopolis in Singapore, it aims to generate new antibody drugs based on Chugai’s proprietary antibody engineering technologies, such as recycling antibody®, sweeping antibody®, bispecific antibody, various Fc engineered antibodies, and other new antibody engineering technologies that are under development.

Position – Senior Scientist in Lead Optimization Unit

CPR is seeking a scientist with expertise in protein engineering.

Job requirements

The applicant should be highly skilled in at least one of the following areas:

• Strong and proven expertise in structural biology and molecular biology for protein structure/function investigation.
• Advance knowledge in protein and/or antibody engineering, including but not limited to rational or random mutagenesis engineering approach.
• Expertise in protein biochemistry, protein expression, purification, and characterization.
• Strong organizational skills to deal with large amounts of data and excellent communication and collaborative skills, as well as a team player mindset for working with cross‑functional multi‑disciplinary teams.
• Knowledge and skill of high‑throughput system, automation, and/or general scripting language is a plus but not a must.
• Knowledge and skill of cell biology, biophysics or immunology is a plus but not a must.

The applicant must have completed and be awarded with a relevant Ph.D. degree in Biomedical Science/Biochemistry/Chemical Biology/Biotechnology/Information science with 1‑2 years of working experience in a related field. In addition, the successful candidates must be able to demonstrate technical expertise in areas which may include molecular biology, cell biology, protein chemistry and protein engineering as evidenced by projects, presentations, or peer‑reviewed scientific publications.

As frequent communication and liaison is expected between both the Singapore and Japan office, you should possess an excellent command of both spoken and written Japanese and English languages.

Interested applicants are invited to email their detailed resume, as well as their qualifications, availability, current and expected salary to: [e-mail].

For more information regarding our Company, you may refer to our website at: http://chugai-pharmabody.com/

We regret that only short‑listed candidates will be notified