Research Assistant

NATIONAL UNIVERSITY OF SINGAPORE; Singapore; On-site; SGD 50,000 - 70,000; Full time

Job summary

A leading educational institution in Singapore is seeking a highly motivated (Senior) Research Assistant to support RNA therapeutics programs, particularly lipid nanoparticle-based delivery. The candidate will handle RNA synthesis/handling and optimize formulations in cardiovascular disease models. A Bachelor's or Master's degree in relevant fields and minimum 2 years of research experience is required. Strong laboratory skills, knowledge of molecular biology techniques, and collaborative spirit is essential for this role.

Qualifications

• Minimum of 2 years of relevant research experience in RNA biology or RNA therapeutics.
• Experience with in vitro assays and/or in vivo animal work preferred.
• Knowledge of cardiovascular and translational research is essential.

Responsibilities

• Support RNA therapeutics programs, particularly LNP formulation and delivery.
• Conduct monitoring, documentation, and reporting of experimental results.
• Prepare presentations, reports, and literature reviews.

Skills

Molecular biology techniques

Laboratory skills

Communication skills

Experimental troubleshooting

Team collaboration

Education

Bachelor’s or Master’s degree in Life Sciences, Biomedical Science, Chemistry, Materials Science

Tools

ELISA

Histology

Job description

Job Description

The Cardiovascular and Metabolic Disorders (CVMD) Programme at Duke-NUS houses state-of-the-art technologies for profiling mitochondrial function, RNA-based therapeutics, and metabolic adaptations in human patients and relevant model systems. The programme undertakes translational and clinical research in cardiovascular and metabolic disorders, with a strong emphasis on therapeutic development, including lipid nanoparticle (LNP)-based RNA delivery platforms.

We are seeking a highly motivated (Senior) Research Assistant to support RNA therapeutics programs, with lipid nanoparticle (LNP) formulation and delivery as a core component of the role. The successful candidate will play a key hands-on role in RNA synthesis/handling, LNP formulation and optimization, and downstream in vitro and in vivo validation in cardiovascular disease models.

• Perform tasks and support all aspects of assigned research projects under the supervision of the Principal Investigator or designate.
• Conduct accurate monitoring, documentation, and reporting of experimental results and research findings.
• Evaluate and interpret data, and prepare oral presentations, written reports, scientific manuscripts, and literature reviews.
• Assist researchers in aspects of project management, laboratory demonstrations, and guidance of undergraduate or medical students.
• Establish and maintain work procedures to ensure high laboratory efficiency, productivity, and compliance with safety protocols.
• Provide technical support, assist with general laboratory upkeep, and support ongoing research projects.
• Perform other related duties incidental to the work described.

Job Requirements

• Bachelor’s or Master’s degree in Life Sciences, Biomedical Science, Chemistry, Materials Science, or related fields.
• Minimum of 2 years of relevant research experience in RNA biology, RNA synthesis, RNA therapeutics, or lipid nanoparticle (LNP) delivery.
• Demonstrated hands-on expertise in molecular biology techniques, cellular assays, ELISA, and/or histology.
• Experience with in vitro assays and/or in vivo animal work (rodents) is preferred.
• Strong laboratory skills with good experimental troubleshooting capability.
• Knowledge of scientific background relevant to cardiovascular and translational research.
• Strong team player with the ability to prioritise, multitask, and work collaboratively in a diverse environment.
• Good communication, documentation, and organizational skills.
• RCULA certification will be an advantage.

We regret that only shortlisted candidates will be notified.