Clinical Research-Jobs in United States

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Client:

Barts Health NHS Trust

London, United Kingdom

Other

Yes

4bd022c59397

2

18.04.2025

02.06.2025

Job overview

This is an exciting opportunity to work in the world-leading Critical Care & Perioperative Medicine Research Group (CCMPG) based jointly at Barts Health NHS Trust and Queen Mary University of London. This unique post combines clinical research activity with the opportunity to further develop leadership and research skills. The successful applicant will play a key role in a diverse multi-professional team of nurses, doctors, allied health professionals and specialist researchers.

They will be responsible for the recruitment and data capture of anthropometric and physical function data for the ASICS II trial across the London trial sites and working with the research team on day-to-day management of the ASICS trial programme of work. They will also be responsible for site education on trial feeding protocols and troubleshooting. They will ensure all projects are run according to Regulatory requirements, guidelines, GCP and to the study protocol. They will liaise frequently with trial chief/principal investigators and the clinicians responsible for patient care. Further responsibilities may be allocated depending on the specific skills that the applicants have and/or wish to develop.

This role is appointable for one year in the first instance, extendable to 36 months.

Main duties of the job

Brief background of ASICS 2

The Alternative Substrates in the Critically Ill Subject-II (ASICS-II) trial

Research question: In critically ill patients, can a 10-day ketogenic enteral feeding regimen increase the number of repetitions in a 30 second sit to stand test 30 days from randomisation, compared to a standard enteral feeding regimen?

Aims/Objectives

1. Primary clinical: To assess the efficacy of the ketogenic feed versus standard feed in increasing sit-to-stand repetitions performed in 30 seconds, 30 days from randomisation in critically ill patients.
2. Secondary clinical: To confirm induction of ketosis by determining between-group serum concentrations of ketone bodies seven-days post randomisation in a blinded fashion.
3. Secondary mechanistic: To examine efficacy along the causal pathway (differential ketone and amino acid flux, urea cycle flux and Tri Carboxylic Acid cycle intermediate generation) using Liquid Chromatography-Mass Spectrometry based targeted metabolomics.

Key result areas

1. Study Delivery of ASICS 2 and other trials within the ASICS programme
2. Education and Training of the multi-professional team at trial sites
3. Clinical/Professional Support of the multi-professional team at trial sites

Working for our organisation

Barts Health is one of the largest NHS trusts in the country, and one of Britain’s leading healthcare providers.

The Barts Health group of NHS hospitals is entering an exciting new era on our improvement journey to becoming an outstanding organisation with a world-class clinical reputation. Having lifted ourselves out of special measures, we now have the impetus and breathing space to chart a fresh course in which we are continually striving to improve all our services for patients.

Our vision is to be a high-performing group of NHS hospitals, renowned for excellence and innovation, and providing safe and compassionate care to our patients in east London and beyond. That means being a provider of excellent patient safety, known for delivering consistently high standards of harm-free care and always caring for patients in the right place at the right time. It also means being an outstanding place to work, in which our WeCare values and behaviours are visible to all and guide us in how we work together.

We strive to live by our WeCare values and are committed to promoting inclusion, where every staff member has a sense of belonging. We value our differences and fully advocate, cultivate and support an inclusive working environment.

Detailed job description and main responsibilities

We are dedicated to being an outstanding place to work and will work with you to get the best experience. We know flexible working is not a one size fits all and will mean something different to everyone. We are inclusive, so if you are interested in flexible working, please speak to the recruiting manager.

Although this position is a 12 months fixed-term contract, the actual contract duration will be adjusted to account for the time taken to advertise the post, complete the hiring process, and finalise pre-employment checks. This means the contract will begin when the candidate starts the role and may be slightly shorter than 12 months.

The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience, and knowledge required. For both documents, please view the attachment/s below.

Informal discussions and visits are welcomed, please contact Priyanthi Dias.

Person specification

Qualifications

• HCPC Registration
• Good Clinical Practice Training

Experience

• Significant clinical experience
• Experience within the intensive care and perioperative environment
• Experience of working on quality improvement projects or clinical trials
• To have contributed to written research papers or conference presentations
• Published in an academic journal
• Experience in critical care survivorship clinical work

Knowledge

• Good Clinical Practice

Skills

• Interest in research and Service innovation
• Computer Literate – Word Excel, PowerPoint, Outlook Access, SPSS
• Demonstration of team working and interpersonal skills
• Knowledge of current professional issues
• Ability to work with all disciplines
• Good organisational skills
• Ability to problem solve and think critically
• Understanding of ‘Good Clinical Practice’ for Clinical Research

Other

• Evidence of research based practice
• Precise and methodical in working practice
• Prepared to develop responsibilities and extend your role
• Ability to prioritise, meet tight deadlines and work independently on a number of projects
• Ability to work in a multi-professional arena
• Ability to lead and manage meetings effectively
• Demonstrable effective team management

Other

• Work and travel between all Bart’s Health NHS Trust sites
• Ability to travel across all Greater London trial sites
• Sufficient to perform the duties of the post with any aids and adaptations
• Able to work under own initiative
• Able to accommodate the demands of the post with flexible working as required
• Proactive and self-motivated with ability to lead, motivate and empower others