Senior Clinical Trials Assistant

University Hospital Southampton NHS Trust; Southampton; On-site; GBP 27,000 - 31,000; Full time

Job summary

A leading healthcare institution in Southampton is seeking a Senior Clinical Trials Assistant to join their research team. This role involves organizing and managing clinical trials, providing direct patient care, and ensuring compliance with regulations. The ideal candidate will have significant experience in a healthcare setting and a related educational background. The position offers a salary range of £27,485 to £30,162 per annum and embodies a commitment to diversity and inclusion.

Qualifications

• Significant relevant experience in a patient-facing healthcare clinical role.
• IT literate in Microsoft Office software including Word and Excel.
• Experience of data management and advanced keyboard skills.

Responsibilities

• Assist in delivering clinical research studies with patient care.
• Coordinate delegated interventional and observational studies.
• Manage own delegated workload efficiently.

Skills

Patient-facing healthcare experience

Data management

IT literacy in Microsoft Office

Clinical research experience

Advanced keyboard skills

Awareness of research governance legislation

Education

A level or equivalent

Care Certificate or NVQ3

Degree or higher education in healthcare

IT related qualifications

ICH-GCP training

Job description

Senior Clinical Trials Assistant

Closing date: 13 January 2026

University Hospital Southampton NHS Foundation Trust is delighted to offer a fantastic opportunity to work with us.

Please see below for detailed job description of the role.

Main duties of the job

We are seeking a motivated and experienced Senior Clinical Trials Assistant to join the Cystic Fibrosis (CF) and Bronchiectasis Research Team within our Clinical Research Facility. This is an exciting opportunity to play a key role in the delivery of high-quality clinical research studies, supporting both participants and the wider multidisciplinary research team.

The post holder will assist in the delivery of clinical research studies, providing direct patient care alongside essential administrative and organisational support. You will be responsible for organising and managing your own workload, including the day-to-day coordination and implementation of delegated clinical trials, ensuring studies are conducted in line with protocols, Good Clinical Practice (GCP), and regulatory requirements.

You will be expected to develop and maintain clinical knowledge and practical skills relevant to the role, enabling you to provide a consistently high standard of care to participants and volunteers taking part in research studies. Working within your scope of competence, you will deliver direct clinical care and undertake a range of clinical tasks and observations. These will include, but are not limited to:

• Venepuncture
• Manual and electronic blood pressure measurement
• ECG recording
• Anthropometric measurements such as height and weight

Job responsibilities

• Assist in the delivery of clinical research studies, providing direct patient care and administrative support
• Coordinate and implement delegated interventional and observational studies on a day-to-day basis
• Organise and manage own delegated workload to ensure studies are delivered efficiently and to protocol
• Undertake participant screening, eligibility checks, and informed consent where appropriately delegated
• Conduct all research activities in accordance with ICH Good Clinical Practice (GCP), legislation, local policies, and study protocols
• Identify, monitor, report, and escalated participant safety concerns and adverse events in line with Trust and research governance requirements
• Coordinate study administration including:
• Booking and preparing participant appointments and visits
• Arranging participant reimbursement for research visits
• Accurately complete trial documentation, data entry, and data queries using approved participant records and IT systems
• Arrange shipment of biological samples, data, and equipment nationally and internationally
• Maintain stock levels of study consumables, ensuring correct storage and timely replenishment
• Act as the first point of telephone contact for research enquiries, providing appropriate clinical and non-clinical information within role boundaries
• Prepare for and support monitoring visits, including documentation preparation and acting as a liaison during visits
• Maintain a clean, safe, and secure environment for participants and staff
• Develop and promote effective working relationships within a multidisciplinary team
• Act as a role model and ambassador for clinical research, supporting and guiding junior staff where appropriate
• Recognise professional boundaries, escalating concerns appropriately and undertaking training to maintain competence
• Participate in and deliver staff training by sharing knowledge and experience
• Provide a flexible service, including 24/7 working as required to meet participant, study, and service needs

About us

University Hospital Southampton is one of England's largest acute teaching Trusts, offering a wide range of learning and development opportunities to support your career aspirations.

Located on the south coast with an international airport and direct rail links to London, Southampton offers an ideal setting to live and work, with the New Forest, South Downs and Jurassic Coast.

At UHS we're committed to providing a flexible working environment where possible. Whether you are balancing family, study, or your wellbeing with your career, we want to support you so you can help our patients.

At UHS, we proudly champion individuality, recognising that outstanding care is only possible with a diverse, inclusive team. We're committed to creating an anti-racist, anti-discriminatory environment where everyone feels valued, safe, and empowered to make a meaningful impact in our communities. We welcome applicants of all backgrounds, identities, and experiences to join us in building a healthcare community where everyone can belong, thrive, and contribute.

Trust Values

• Always Improving
• Working Together

Qualifications / training required

• Educated to ‘A’ level or equivalent
• Complete Care Certificate or NVQ3 / foundation degree in Healthcare-related subject
• Evidence of continuing professional development
• Degree / higher education or equivalent
• IT related qualifications
• ICH-GCP trained

Previous or relevant experience necessary

• Significant relevant experience in a patient‑facing healthcare clinical role
• IT literate in Microsoft Office software (including Word and Excel)
• Experience of data management
• Advanced keyboard skills
• Clinical research experience
• Knowledge of case note tracking, computerised patient administrative systems
• Awareness of current legislation regarding research governance issues
• Acute hospital experience

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

University Hospital Southampton NHS Trust

£27,485 to £30,162 a year Per Annum (PA) Pro Rata