Scientist - Cell Biology

SLS Services Limited; Cambridge; On-site; GBP 40,000 - 60,000; Full time

Job summary

A biotechnology company in Cambridge is seeking a research scientist to develop next-generation iPSC-derived cell therapies. The role involves designing complex research programs, developing flow cytometry assays, and mentoring junior lab members. Ideal candidates will have a PhD or MSc with relevant experience and expertise in cell therapies.

Qualifications

• Relevant experience in either industry or academia required.
• Expertise in developing and applying flow cytometry methods.
• Experience with FACS and cell sorting techniques.

Responsibilities

• Design and execute complex research programs in cell biology and iPSC-derived therapeutics.
• Develop, optimize, and perform flow cytometry assays.
• Mentor junior lab members in experimental techniques.

Skills

Flow cytometry methods

FACS techniques

In vitro methods for immune profiling

iPSC differentiation and culture

Single-cell technologies

Education

PhD or MSc

Job description

This exciting opportunity is focused on developing next-generation iPSC-derived cell therapies to address challenges faced by current approaches. In this role, you will play a pivotal role in the characterization and culture of iPSCs, helping to advance novel technologies in human therapeutics.

The technology employed enables the development of stable, adaptable, and programmable gene silencing, distinguishing it from traditional gene-editing approaches. This innovation aims to overcome current limitations in cell therapies by engineering allogeneic approaches that are activated in response to specific environmental cues, both intracellular and extracellular. The technology is complemented by computational and screening platforms to target preferred genetic modifications.

Key Responsibilities:

• Design and execute complex research programs in the area of cell biology and iPSC-derived therapeutics.

• Develop, optimize, and perform flow cytometry assays for cell characterization.

• Design, develop, and conduct FACS (Fluorescence-Activated Cell Sorting) experiments.

• Apply in vitro assays for immune cell biology profiling.

• Develop and optimize methods for the differentiation and culture of iPSCs.

• Mentor junior lab members and guide them in experimental techniques.

• Stay up-to-date with advancements in the field and explore new technologies to improve methodologies.

Desired Skills and Experience:

• PhD or MSc with relevant experience in either industry or academia.

• Expertise in developing and applying flow cytometry methods.

• Experience in FACS and cell sorting techniques.

• Experience with the differentiation and culture of iPSCs or other stem cell types.

• Proficiency in in vitro methods for immune cell profiling.

• Familiarity with single-cell technologies for cell therapy profiling or immune cells is advantageous.