Principal Scientist PKPD

Proclinical; Reading; On-site; GBP 60,000 - 80,000; Full time

Job summary

A life sciences recruiting agency in Reading seeks a Principal Scientist PKPD to advance oncology projects. You will develop non-clinical PKPD strategies, ensure quality data for regulatory submissions, and collaborate with cross-functional teams. Ideal candidates have a strong background in pharmacology and PKPD data analysis, with excellent communication skills. This role involves leading projects and generating high-quality reports.

Qualifications

• Strong understanding of pharmacology and drug mechanisms related to disease.
• Proven ability to design and analyze non-clinical PKPD studies.
• Experience in matrix environments and managing multiple projects.

Responsibilities

• Lead non-clinical PKPD and regulatory studies.
• Design protocols and communicate data analysis results.
• Deliver regulatory-standard data packages.

Skills

Quantitative pharmacology

Pharmacokinetics/pharmacodynamics (PKPD)

Communication skills

Data analysis

Education

PhD/MSc/BSc in relevant field

Tools

Phoenix WinNonlin

Berkeley Madonna

R

Job description

Overview

Proclinical is seeking a Principal Scientist PKPD to join a dynamic team in the oncology and pharmaceutical space. This role focuses on driving non-clinical pharmacokinetics and pharmacodynamics (PKPD) strategies, supporting early clinical development, and contributing to regulatory submissions. You will collaborate with cross-functional teams to deliver high-quality data packages and play a key role in advancing drug candidates.

Responsibilities

• Develop and lead non-clinical PKPD and GLP toxicokinetics study strategies.
• Design and write protocols for regulatory studies, providing scientific input.
• Collaborate with project teams and CROs to ensure high-quality data generation.
• Work under GLP compliance to deliver regulatory-standard data packages.
• Communicate interim and final PKPD-toxicokinetic data analysis results to stakeholders.
• Deliver comprehensive PKPD study reports and contribute to submission documents.
• Build a thorough understanding of drug pharmacology and PKPD to facilitate candidate advancement.
• Represent the department internally and externally, enhancing its scientific reputation.

Qualifications

• Background in quantitative pharmacology, pharmacokinetics/pharmacodynamics, or DMPK (PhD/MSc/BSc).
• Hands-on experience in PKPD data analysis within a pharma or CRO environment.
• Strong understanding of pharmacology and drug mechanisms related to disease.
• Proven ability to design, execute, and analyze non-clinical PKPD studies, including GLP toxicokinetics.
• Proficiency in Phoenix WinNonlin for PKPD analysis; familiarity with tools like Berkeley Madonna or R is a plus.
• Excellent communication skills, with the ability to produce high-standard reports for regulatory submissions.
• Experience working in matrix environments and managing multiple projects simultaneously.
• A record of publications or external scientific contributions in PKPD is advantageous.

If you are having difficulty in applying or if you have any questions, please contact Joshua Bye at [e-mail].

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