Large Molecule Bioanalytical Manager

Roche; Plymouth; On-site; GBP 65,000 - 85,000; Full time

Job summary

A leading global healthcare company is seeking a Large Molecule Bioanalytical Manager in Plymouth. This role involves leading bioanalytical strategies for innovative therapies and managing outsourcing while ensuring compliance with regulations. Ideal candidates are strategic thinkers with a strong technical background in bioanalysis. Join a mission to deliver effective medicines and improve outcomes for patients worldwide.

Qualifications

• Significant experience in regulated bioanalysis including large and small molecules.
• Proven ability to oversee CROs ensuring quality and compliance.
• Strong leadership and cross-functional collaboration.

Responsibilities

• Lead regulated bioanalytical strategies to generate decision-enabling data.
• Manage bioanalytical outsourcing for studies.
• Ensure compliance with bioanalytical guidance and GxP.

Skills

Regulated bioanalysis

Leadership in project delivery

Collaboration

Customer-centric thinking

Continuous improvement mindset

Education

Degree or Master’s in Life Sciences

PhD in relevant field

Job description

Overview

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Opportunity

At Roche, within the Pharmaceutical Research and Early Development organisation, we transform science into medicines that change lives. You’ll be embedded in a culture defined by curiosity, collaboration, and purposeful innovation — where science is rapidly transformed into life-changing therapies.

We’re looking for Large Molecule Bioanalytical Managers to join our Regulated Bioanalysis and Biosample Operations chapter within Roche’s Pharmaceutical Sciences function. This position is based either in Welwyn (North London) or Basel. This is your chance to lead regulated bioanalytical strategies across large molecule programs, driving scientific and operational excellence to deliver better outcomes for patients.

In this high-impact role, you’ll:

• Lead regulated bioanalytical strategies (PK, Immunogenicity and Biomarkers) to generate decision-enabling data


• Manage bioanalytical outsourcing for non-clinical and clinical studies


• Guide assay validation and sample analysis from development through post-marketing


• Ensure full compliance with global/local bioanalytical guidance and GxP


• Collaborate across project teams, CROs, and internal stakeholders to deliver a robust bioanalytical data package for regulatory submissions


• Champion innovation and foster a collaborative, hierarchy-free chapter culture

Who You Are

You are a strategic thinker with strong technical expertise and thrive in a collaborative, fast-paced environment.

• A degree or master’s (PhD is a plus) in life sciences and significant experience in regulated bioanalysis including large and small molecules, gene therapies, oligonucleotides and ADCs. Gene Therapies would be a real advantage.


• Proven ability to oversee CROs and ensure scientific quality and regulatory compliance


• A mindset of continuous improvement — you welcome feedback and support others’ growth


• Strong leadership in project delivery, cross-functional collaboration, and customer-centric thinking


• A bold, patient-first approach — focusing only on what delivers value

Join us to rethink how bioanalysis enables the delivery of safe, effective medicines — and accelerate better outcomes for patients everywhere.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

The statements herein are intended to describe the general nature and level of work being performed by employees, and are not to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. Furthermore, they do not establish a contract for employment and are subject to change at the discretion of Roche Products Ltd. At Roche Products we believe diversity drives innovation and we are committed to building a diverse and flexible working environment. All qualified applicants will receive consideration for employment without regard to race, religion or belief, sex, gender reassignment, sexual orientation, marriage and civil partnership, pregnancy and maternity, disability or age. We recognise the importance of flexible working and will review all applicants’ requests with care. At Roche difference is valued and we are proud to be an equal opportunity employer where you are encouraged to bring your whole self to work.