Early Phase CTAP Clinical Research Practitioner

Guy's and St Thomas' NHS Foundation Trust; City Of London; On-site; GBP 60,000 - 80,000; Full time

Job summary

A leading healthcare organization in London is seeking a specialist to focus on early phase clinical trials for cystic fibrosis (CF). The role involves coordinating with local clinical teams, optimising trial processes, and leading mentorship initiatives. Candidates should have experience in clinical trial operations and be able to facilitate collaborations across various centres. This position also supports professional development within a dynamic research environment.

Benefits

Support for career progression

Access to courses and conferences

Qualifications

• Experience in clinical trial operations and management.
• Strong communication and collaboration skills.
• Ability to mentor and train others in clinical trial processes.

Responsibilities

• Support delivery of early phase CF clinical trials.
• Facilitate research referrals and collaboration.
• Lead training and mentorship initiatives.

Job description

Overview

This specialist role focuses on early phase CF trials, working alongside the existing CTAP Trial Coordinator and integrating into the local clinical and research teams to improve trial access for the CF community.

The Postholder Will Work Closely With

• Local CF Clinical and Research Teams – to coordinate and deliver early phase CF trials within the Trust.
• CTAP Trial Coordinator – to ensure alignment and collaboration across early and later phase trials.
• CTAP Programme Team (Cystic Fibrosis Trust) – for strategic guidance, reporting, and network-wide coordination.
• Other CTAP Early Phase Centres and Affiliate Sites – to facilitate referrals, share best practices, and support national trial delivery.
• Research & Development Departments – to ensure compliance with governance and regulatory requirements.
• Trial Sponsors and CROs – to support trial setup, feasibility, and ongoing delivery.
• Patients and Families – to provide information, support, and facilitate participation in clinical trials.
• Training and Education Leads – to deliver mentorship and training to other CTAP centres preparing for early phase trial readiness

Key Responsibilities Include

• Supporting the delivery of early phase CF clinical trials within the CTAP Early Phase Sub-Network.
• Optimising use of the CTAP Patient Identification Centre (PIC) model.
• Facilitating research referrals in collaboration with other CTAP Centres, Affiliate Centres, and CF units.
• Leading training, mentorship, and education initiatives to help other CTAP centres become ‘phase 1 ready’.
• Assisting with later phase CF trials locally during quieter periods. Contributing to non-CF early phase trials to support professional development and broaden early phase trial experience.

This post is based within the Royal Brompton Cystic Fibrosis (CF) Clinical Trials Department, a multidisciplinary team of clinicians, academics, allied health professionals, and administrative staff. Led by Professors Davies, Simmonds, and colleagues, the adult and paediatric CF centres conduct internationally recognised, multicentre interventional and observational studies across all age groups. The department plays a key role in early phase research through its involvement in the CF Trusts CTAP Early Phase Sub-Network (https://www.cysticfibrosis.org.uk/research/clinical-trials/clinical-trials-accelerator-platform), a specialist group of centres established by the Cystic Fibrosis Trust to lead early phase CF trials across the UK. With CF care advancing rapidly and new treatments emerging, access to clinical trials is increasingly vital. CTAP supports trial sponsors and CF centres in the setup and delivery of studies across a network of 20 centres, including Guy’s & St Thomas’ NHS Trust. Based near the vibrant King’s Road in Chelsea, this role offers excellent opportunities for collaboration and professional development within a dynamic clinical and research environment.

We encourage and support applicants in applicable career progression as a clinical research practitioner/research nurse including attendance at courses, seminars and conferences.

For further details / informal visits contact: Name: Clare Saunders Job title: Research Service Lead Email address: [e-mail]