Wet-lab Postdoc in Evolutionary Functional Genomics

Inserm UA12; France; Sur place; EUR 35 000 - 50 000; Plein temps

Résumé du poste

A leading research institution in France seeks a postdoctoral researcher to explore rapid evolution mechanisms in mammals. The successful candidate will work on a funded project focusing on the uterus evolution, employing techniques like single-cell sequencing and CRISPR. Applicants should have a background in cell biology and strong communication skills. Flexible start date from April 2026. Salary adjusted to experience.

Prestations

Fully funded position for 2 years

Diverse collaboration opportunities

State-of-the-art facilities

Qualifications

• Enthusiastic scientist with a strong background in cell or developmental biology.
• Willingness to learn new skills from training programs.

Responsabilités

• Explore functional mechanisms of rapid evolution in mammals.
• Conduct single-cell multi-omics of fresh tissues and organoid models.
• Collaborate to develop postdoctoral projects fitting your skills and interests.

Connaissances

Primary cell culture

Organoids

Single-cell sequencing

Functional genomics wet-lab techniques

CRISPR-Cas9 editing techniques

Excellent communication skills

Excellent organizational skills

Description du poste

Organisation/Company Inserm UA12 Department UA12 Research Field Biological sciences Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Country France Application Deadline 1 Apr 2026 - 23:59 (Europe/Paris) Type of Contract Temporary Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The Berthelot lab at Institut Pasteur in Paris has an opening for a postdoctoral researcher to join our team on a 2M€ grant project to explore the functional mechanisms of rapid evolution in mammals.

Our team focuses on the uterus, a fascinating yet understudied organ in mammals. Despite its central role in mammalian reproduction, the uterus evolves very rapidly, driven by a continuous evolutionary crosstalk to optimize maternal/embryonic interactions. We want to understand how uterine gene expression programs have repeatedly evolved to produce dramatic phenotypes such as menstruation or invasive embryo implantation – two rare traits that appeared during primate evolution, but have also evolved independently in other mammalian groups. To answer these exciting questions, we perform single-cell multi-omics of fresh tissues and organoid models of the uterine mucosa across humans, primates and mammals.

You will join a multidisciplinary, highly collaborative lab and will have flexibility to address varied biological questions within our core project. The postdoctoral project will be developed in collaboration with the candidate to fit your skills and interests.

We are seeking an enthusiastic scientist with a strong background in cell or developmental biology and at least some of the following skills:

• Proficient with primary cell culture, organoids, assembloids or explant culture
• Prior experience with single-cell sequencing or functional genomics wet-lab techniques
• Prior experience with CRISPR-Cas9 editing techniques
• Excellent communication and organizational skills

However, training can be offered in any of these skills as part of the Institut Pasteur training programs and in collaborations with other team members.

Languages ENGLISH Level Excellent

Research Field Biological sciences » Biology

Additional Information

Funding

The position is fully funded for 2 years with possibilities for extension. The lab benefits from excellent support thanks to several ongoing grants and Institut Pasteur core funding.

Salary will be commensurate to experience following the Inserm pay scale. Start date is flexible from April 2026.

The Berthelot lab is a G5 tenure-track group at Institut Pasteur, situated in the heart of Paris, France. We are part of the Genomes and Genetics department and have co-affiliations to the Developmental and Computational Biology departments, providing our lab members with diverse opportunities to collaborate and receive feedback. We offer an outstanding scientific environment, with access to state-of-the-art experimental and computational facilities, excellent technical support, a diverse network of collaborators, and an exciting international environment within the Institut Pasteur, one of the leading biomedical research institutions worldwide. We are also committed to providing our lab members with a supportive environment where creativity, openness and kindness are encouraged.

Selection process

Send a motivation letter with your CV, list of publications and the contact information of at least two references to Camille Berthelot: [e-mail] .

Application reviews will begin immediately, until a suitable candidate is found. Latest deadline for applications is 1 April 2026.

For any questions, please reach out to Camille.