Senior Cheminformatics Engineer

AstraZeneca; Barcelona; Híbrido; EUR 60.000 - 80.000; Jornada completa

Descripción de la vacante

A leading biopharmaceutical company in Barcelona is seeking a Senior Cheminformatics Engineer to build and enhance scientific solutions in drug discovery. The role requires expertise in cheminformatics tools and software engineering skills, along with collaboration in an agile team. You will shape the technical direction and engage with stakeholders, making a significant impact on drug development. Flexibility in work arrangements is offered, promoting both office presence and individual choice.

Formación

• Expertise in cheminformatics toolkits is required.
• Strong understanding of drug discovery and DMTA cycle.
• Deep knowledge of chemistry data models required.
• Experience in software development and problem-solving.
• Skills in software engineering including Python and Java.

Responsabilidades

• Build scientific solutions for drug discovery using cheminformatics.
• Collaborate with scientists and engineers in an agile team.
• Influence technical direction across the cheminformatics platform.

Conocimientos

Cheminformatics toolkits (e.g., RDKit, CDK)

Understanding of drug discovery processes

Chemistry data models

Software development for drug discovery

Programming in Python, Java, JavaScript

Building production-grade solutions

SQL / NoSQL database management

Exceptional communication skills

Software engineering practices

Descripción del empleo

Overview

Introduction to role

AstraZeneca is seeking a Senior Cheminformatics Engineer to expand its Augmented Design-Make-Test-Analyse (A-DMTA) platform (R&D IT) in Barcelona. In this role, you will contribute to and help shape the evolution of our cheminformatics software and platforms, setting technical direction and enabling scalable, data-driven drug discovery across R&D. You will also take broader responsibility for influencing technical direction across the platform and work in close contact with science stakeholders to shape drug discovery software and data products.

Responsibilities

As Senior Cheminformatics Engineer, you will be responsible for building scientific solutions for small-molecule and new modalities drug discovery, leveraging your expertise in cheminformatics and software engineering. You will be working within an agile, matrixed team of scientists, software and DevOps engineers, architects, BAs, and other cheminformaticians.

Essential Skills/Experience

• Expert in using one or more cheminformatics toolkits (e.g., RDKit, CDK, OpenEye, Biovia, Chemaxon)
• Understanding of drug discovery processes and data, with a particular emphasis on the DMTA cycle and the software products used in it
• Deep understanding of chemistry data models, structure standardization rules for small molecules and new modalities (e.g., PROTACs, peptides, oligos)
• Experience of developing novel software to complex drug discovery problems
• Strong software engineering skills in one or more coding languages (e.g. Python, Java, JavaScript)
• Experience building production-grade solutions managing end-to-end Software Development Life Cycle
• Strong experience with developing backend services and their deployment and integration, preferably in the cloud
• Experience using one or more SQL / NoSQL databases and a solid knowledge of query optimisation techniques
• Exceptional communication skills to present and demonstrate your work to stakeholders and end-users
• Practical experience applying good software engineering practices – documentation, versioning, testing, code quality review, CICD, etc.

Desirable Skills/Experience

• Experience using coding agents within IDEs
• Demonstrated contribution to open-source libraries
• Experience building and maintaining chemistry data pipelines
• DevOps specifically in the context of chemistry systems
• Understanding of software and algorithms used in drug design and predictive AI
• Ability to explain complex methods & techniques to non-expert audiences
• Experience working in agile delivery teams

Working at AstraZeneca

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca

Here you will blend cutting-edge science with leading digital technologies to deliver real-world impact on the pace and quality of medicine discovery. We bring diverse experts together to spark bold thinking, back them with significant investment, and empower them to take ownership from idea to implementation. You will explore new technologies, build scalable platforms that the business relies on daily, and grow through shared learning, open collaboration, and the satisfaction of seeing your work unlock better decisions for scientists and better outcomes for patients.

If you are ready to turn advanced cheminformatics and engineering into faster, smarter discovery for patients, step forward and make your mark today!

Dates

Date Posted 27-ene-2026

Closing Date 09-feb-2026

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.