Scientist - Process Development

MEDPHARM LTD; Guildford; On-site; GBP 25,000 - 35,000; Full time

Job summary

A pharmaceutical development company based in Guildford is seeking a laboratory technician to execute process development and scale-up of semi-solid products. Candidates should possess a BSc in a relevant field and ideally have 1 to 2 years of relevant experience. Responsibilities include performing GxP compliant experiments, maintaining laboratory standards, and ensuring safety policies are followed. The ideal candidate should be solution-focused, possess strong attention to detail, and have problem-solving skills. This position offers the opportunity to work in a dynamic environment and develop professionally.

Qualifications

• 1 to 2 years relevant experience is desirable.
• Knowledge of emulsions and excipients is important.
• Experience in testing according to a monograph is beneficial.

Responsibilities

• Execute process development and scale-up of semi-solid products.
• Perform experiments in compliance with GxP regulations.
• Maintain confidentiality and adhere to safety policies.
• Assist in the smooth running of laboratory activities.

Skills

Solution-focused

Attention to detail

Problem solving

Ability to work independently and within a team

Education

BSc in a relevant field

Job description

Responsibilities

• Execute process development and scale-up of semi-solid products within the set timeframe.
• Perform pre-defined experiments according to the study plan and in compliance with GxP regulations and MedPharm's QMS.
• Adhere to MedPharm ethos and comply with the SOPs, policies and QMS systems.
• Maintain confidentiality of information and data.
• Execute projects in accordance with the study documentation, experimental designs, and SOPs, in agreed timelines and in compliance with MedPharm's QMS.
• Maintain cross‑functional communication with the internal stakeholders of the project(s) being worked on.
• Review literature (including equipment operating procedures) in preparation for studies and regularly update knowledge by reading appropriate literature and / or attending appropriate training courses / webinars.
• Manufacture and fill formulations as required for the stage of the project, including but not limited to, working on BMRs to provide toxicology batches in Process Development and clinical batches in GMP.
• Characterise formulations during different project phases.
• Communicate the progress of studies to the Team Leader / Senior Scientist / Study Manager as appropriate and other internal stakeholders where required.
• Assist with data input for written project updates.
• Attend and contribute to internal project meetings as required.
• Plan and organise the work with a degree of autonomy with due consideration to the resources.
• Report any amendments and deviations from SOPs and study plans / testing protocols to Team Leader / Senior Scientist / Study Manager as appropriate.
• Ensure that all activities are carried out in line with MedPharm's Health and Safety policy and COSHH regulations to ensure the safety of themselves and others in any procedures or tasks performed.
• Assist other team members as and when required to complete project work.
• Assist in the smooth running of laboratory activities and maintenance of laboratory standards in compliance with MedPharm's QMS.
• Undertake general waste disposal and contribute to the general tidiness and cleanliness of the laboratory environment.
• Maintain training records.
• Be sufficiently trained to undertake GMP activities on request.

Supervisory Responsibilities

None

Key Relationships

• Departmental Scientists of all grades
• Study Directors
• Head(s) of Department
• Technicians
• Quality Assurance
• Project Managers
• 3rd party suppliers

Education & Experience

• BSc in a relevant field
• 1 to 2 years relevant experience (desirable)

Knowledge, Skills & Abilities

Knowledge

• Emulsions
• Excipients
• Testing according to a monograph, e.g., USP
• Moving through different scales of manufacture

Skills

• Solution‑focused
• Attention to detail
• Problem solving
• Ability to work independently and within a team

Physical Demands and Work Environment

• Regularly required to walk within production and laboratory areas.
• May be required to stand for extended periods.
• Exposure to cleanroom environments and temperature‑controlled zones.