Programme Manager

RBW Consulting; Remote; GBP 70,000 - 90,000; Full time

Job summary

A leading biotech start-up is seeking an experienced Programme Manager for a remote role requiring strong abilities in coordinating development programs through CMC and preclinical phases. Candidates should have over 5 years in project management within biotech or CRO environments and demonstrate strong vendor management skills. This is a unique opportunity to operate in a fast-paced environment, ensuring compliance and aligning with regulatory standards while driving critical projects forward.

Qualifications

• 5+ years as a Programme/Project Manager in biotech or CRO environments.
• Proven experience coordinating CMC and/or preclinical development programmes.
• Strong CRO/vendor management across multiple concurrent workstreams.

Responsibilities

• Drive the integrated development plan for CMC, preclinical, and IND phases.
• Track budgets, Gantt charts, and deliverables.
• Liaise with regulatory consultants for programme alignment.

Skills

Programme / Project Management

CRO / Vendor Management

Budget Management

Communication Skills

Organisational Discipline

Job description

Programme Manager

Location : Remote (UK) – occasional face-to-face meetings

Start : ASAP

Reports to : CEO

Status : Full-time

About the Role

We are seeking an experienced Programme Manager to lead and coordinate an accelerated development programme through CMC, preclinical, and IND-enabling phases. This is a unique opportunity to join a fast-moving biotech start-up in its build phase, driving execution across multiple CROs and workstreams.

The role is remote , requiring a highly flexible, hands‑on approach and the ability to operate beyond rigid functional boundaries.

Key Responsibilities

Programme Leadership

• Maintain and drive the integrated development plan (CMC → PK → tox → IND).
• Own critical path, dependencies, risks, and mitigation strategies.
• Lead weekly operational cadence across internal teams and CROs.
• Adapt execution structure as the programme scales.

Vendor & CRO Management

• Manage interactions with CROs across CMC, enzyme engineering, PK / PD, and in‑vivo studies.
• Oversee SOWs, change orders, deliverables, budgets, and issue escalation.
• Ensure structured communication and alignment across all vendors.

CMC & Preclinical Coordination

• Coordinate execution across analytics, linker / payload activities, formulation strategy, biodistribution, PK studies, and GLP tox planning.

Timeline, Budget & Documentation

• Own Gantt charts, budget tracking, and deliverable logs.
• Ensure complete documentation and data‑room organisation.
• Prepare operational materials for investors, advisors, and Board.

Regulatory Readiness

• Coordinate packages and timelines supporting IND‑enabling activities.
• Liaise with regulatory consultants to ensure programme alignment.

Build‑Phase Flexibility

• Operate effectively in a lean, high‑intensity start‑up environment.
• Contribute to establishing processes, templates, and operational cadence.
• Comfortable working outside narrow functional boundaries when needed.

Candidate Profile

Essential Experience

• 5+ years as a Programme / Project Manager in biotech or CRO environments.
• Proven experience coordinating CMC and / or preclinical development programmes.
• Strong CRO / vendor management across multiple concurrent workstreams.
• Experience managing complex development timelines and budgets.
• Familiarity with biologics / ADC / large molecule workflows.

Desirable Experience

• Exposure to ADCs or antibody‑based therapeutics.
• Experience in early‑stage or lean biotech settings.
• Contribution to IND‑enabling packages.

Personal Attributes

• Highly structured, delivery‑focused, and operationally rigorous.
• Independent, proactive, and comfortable with ambiguity.
• Strong communicator with excellent organisational discipline.
• Thrives in a remote‑first, high‑accountability environment.

Ready to take ownership of a high‑impact development programme and help bring first‑in‑class therapeutics to patients?

Apply now by sending your CV today!