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Researcher position (M/F) on a fixed-term contract: Design of a new-generation surgical adhesive

CNRS

France

Sur place

EUR 30 000 - 40 000

Plein temps

Aujourd’hui
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Résumé du poste

A research organization in France is seeking a full-time First Stage Researcher to develop a next-generation surgical adhesive aimed at treating severe traumatic wounds. Candidates must hold a PhD and possess expertise in chemical synthesis and macromolecular characterization. Responsibilities include modifying natural macromolecules and characterizing their properties. The role offers a dynamic environment for innovation and aims to advance medical applications for emergency situations, starting on 30 Mar 2026.

Qualifications

  • Must hold a PhD and have experience at the interface between chemistry and biology.
  • Proficiency in chemical synthesis (organic and natural and synthetic polymers).
  • Ability to read and communicate in English.

Responsabilités

  • Conduct chemical modifications of natural macromolecules.
  • Shape polymers into pastes, sprays, and nanofibers.
  • Characterize physicochemical, mechanical, and degradation properties.

Connaissances

Chemical synthesis
Macromolecular characterization
Cell culture
Communication skills
Organizational skills
Innovative thinking

Formation

PhD in Chemistry or related field

Outils

Electrospinning equipment
Photorheometer
Description du poste

Organisation/Company CNRS Department Institut des Biomolécules Max Mousseron Research Field Chemistry Physics Technology Researcher Profile First Stage Researcher (R1) Country France Application Deadline 25 Dec 2025 - 23:59 (UTC) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 30 Mar 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

This project aims to develop a new-generation surgical adhesive for the rapid and effective treatment of severe traumatic wounds, particularly in civil or military emergency situations. This new system aims to combine strong adhesion in wet environments, on-demand UV activation, controlled biodegradation, and wound healing stimulation properties. The formulation is based on a hybrid macromolecular system combining natural molecules (anti-inflammatory and pro-scarring), both multifunctionalized to be activated on demand. These molecules will be chemically modified to modulate the hydrophilic/hydrophobic balance, allowing the formulation (paste, spray, or nanofibers) to be adapted to clinical needs, paving the way for new galenic forms. Different formats (single-use tube, spray, or nanofibers) will be offered to enable rapid application tailored to the nature of the wound, thereby helping to reduce the sequelae of open wounds outside the operating room.

Responsibilities
  • Chemical modification of natural macromolecules (click chemistry, grafting of photosensitive groups)
  • Polymers shaping: pastes, sprays, and nanofibers (electrospinning)
  • Characterization of physicochemical, mechanical, and degradation properties (photorheometer, adhesion force, swelling, degradation, etc.)
  • Biological evaluation: adhesion, proliferation, and extracellular matrix synthesis capacity of human fibroblasts
Qualifications
  • Motivated, hard-working, capable of conducting rapid research and working independently in a team-oriented environment.
  • Demonstrate innovation, organizational skills, and communication skills.
  • Must hold a PhD and have experience at the interface between chemistry and biology.
  • Proficiency in chemical synthesis (organic and natural and synthetic polymers).
  • Macromolecular and shaped object characterization.
  • Shaping: Electrospinning, for example.
  • Cell culture.
  • Motivation to solve scientific problems.
  • Ability to read and communicate in English.
  • Excellent writing and summarizing skills.
  • Experience in biomedical adhesives would be a plus.
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