Postdoctoral researcher (M/F) - host-pathogen interactions.

CNRS; France; Sur place; EUR 35 000 - 50 000; Plein temps

Résumé du poste

Une organisation de recherche nationale en France recrute un chercheur expérimenté pour contribuer à des études sur les mécanismes de virulence des bactéries pathogènes comme Shigella et Neisseria. Le candidat idéel devra avoir une expérience en interactions hôte-pathogène, être expert en microscopie à fluorescence et avoir des compétences en cytométrie en flux. Ce poste à temps plein est basé à l'IBMC et offre des ressources complètes pour mener à bien la recherche.

Prestations

Accès à la plateforme de l'Institut Pasteur

Bureau et équipements informatiques fournis

Formation des étudiants et stagiaires

Qualifications

• Expérience préalable dans les interactions hôte-pathogène et le processus de coagulation.
• Expertise en microscopie à fluorescence; la maîtrise de la vidéomicroscopie à fluorescence serait appréciée.
• Expertise en cytométrie en flux (cellules immunitaires in vivo).

Responsabilités

• Effectuer des recherches indépendantes sur le sujet choisi.
• Concevoir, réaliser et interpréter des expériences.
• Présenter les résultats à la communauté scientifique.
• Rédiger et publier des articles scientifiques.

Connaissances

Interactions hôte-pathogène

Microscopie à fluorescence

Cytométrie en flux

Expérience en expérimentation animale

Anglais scientifique (niveau B2)

Pratiques de recherche éthiques

Expérience internationale

Formation

Doctorat en biologie

Outils

Microscope de fluorescence

Instruments de laboratoire

Description du poste

Organisation/Company CNRS Department Architecture et Réactivité de l'ARN Research Field Biological sciences Medical sciences Pharmacological sciences Researcher Profile First Stage Researcher (R1) Country France Application Deadline 24 Dec 2025 - 23:59 (UTC) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 2 Mar 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

As part of the ANR Bactoclot project (2025–2028), the laboratory of Dr. Benoit Marteyn (IBMC, CNRS Unit 9002) is recruiting a full-time experienced researcher to contribute to studies on the virulence mechanisms of Shigella, Neisseria, and E. coli. The selected candidate will identify the molecular mechanisms involved in the dissemination of pathogenic bacteria into the bloodstream, despite activation of the complement and coagulation systems.

The project will be carried out at the Institute of Molecular and Cellular Biology (IBMC, University of Strasbourg) in collaboration with a partner at the Institut Pasteur, the laboratory of Dr. Guillaume Dumenil, where intravital imaging approaches will be performed.

• Conduct independent research on the chosen topic
• Design, perform, and interpret experiments
• Present results to the scientific community
• Write and publish scientific articles
• Communicate findings at national and international conferences
• Mentor students and supervise the writing of reports and manuscripts
• Supervise and train interns and PhD students

The position is based at the IBMC, located on the campus of the University of Strasbourg (close to the city center, easily accessible by public transport, with access to university dining facilities). The IBMC is a CNRS institute, part of the French national research organization employing 30,000 researchers. It hosts more than two hundred researchers, faculty members, engineers, technicians, postdoctoral fellows, and Master's or PhD students. The IBMC comprises 20 research teams, with main research areas in infection, immunity, and biochemistry.

As part of the project, assignments will be carried out at the Institut Pasteur and will be fully covered. Access to videomicroscopy in a BSL-2 environment is provided, as well as access to the Institut Pasteur platforms.

All necessary resources will be provided (office space, computing equipment, instrumentation), including a bench in a laboratory.

The initial contract is for 1 year and may be renewed for up to 3 years.

• Previous experience in host–pathogen interactions and the coagulation process
• Expertise in fluorescence microscopy; proficiency in fluorescence video microscopy would be appreciated
• Expertise in flow cytometry (in vivo immune cells)
• Experience in animal experimentation
• Proficiency in scientific English (B2 level)
• Ability to follow ethical research practices
• Previous international experience