Postdoctoral Researcher in Protein NMR (M/F)

CNRS; France; Sur place; EUR 40 000 - 60 000; Plein temps

Résumé du poste

A leading research organization in France is seeking a postdoctoral researcher to apply innovative isotope labelling and NMR methods in studying large molecular complexes. Candidates should possess a PhD in relevant fields, expertise in protein expression and purification, and proficiency in solution NMR spectroscopy. The role involves collaborative research, co-supervision of students, and contributions to publications within a diverse research group. Competitive full-time position with opportunities for significant scientific contributions.

Qualifications

• Candidates must hold a PhD in chemistry, biochemistry or structural biology (or a related discipline).
• Experience of protein expression and purification.
• Experience in protein structural and dynamics studies using solution NMR spectroscopy.
• Ability to conceptualise, creativity, scientific curiosity, sense of innovation.
• Good communication (written/oral) and teaching skills.
• Team spirit.
• C2 level English (written/oral).

Responsabilités

• Work on the application of innovative isotope labelling and NMR methods.
• Development of isotope labelling protocols.
• Cell-free expression of proteins and purification for NMR studies.
• NMR characterization of large complexes.
• Functional studies of large protein complexes.
• Co-supervision of students.
• Publications writing.
• Participate in the life of the research group.

Connaissances

Protein expression and purification

Solution NMR spectroscopy

Good communication skills

Team spirit

C2 level English

Formation

PhD in chemistry, biochemistry or structural biology

Description du poste

Organisation/Company CNRS Department Institut de biologie structurale Research Field Biological sciences Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Country France Application Deadline 29 Dec 2025 - 23:59 (UTC) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 1 Apr 2026 Is the job funded through the EU Research Framework Programme? Not funded by the EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The successful candidate will work on the application of innovative isotope labelling and NMR methods to the study of large molecular complexes and machines of medical importance, as part of the European ERC advanced grant XXL-NMR project.

• Development of isotope labelling protocols
• Cell-free expression of proteins and purification for NMR studies
• NMR characterization of large complexes
• Functional studies of large proteins complexes
• Co-supervision of students
• Publications writing
• Taking part in the life of the research group (contributing to logistics, monitoring stocks of reagents, etc.)

Located on the Grenoble science campus (ESRF/ILL/EMBL/IBS), the structural biology institute (IBS) is a leading national and international research institute in the field of integrated structural biology. The IBS is a research center, a technical infrastructure, a host site and a scientific training center. Its mission is to develop research in structural biology, a crucial field for understanding fundamental biological mechanisms. It is supported by 12 state-of-the-art facilities, including high field NMR facility equipped with 950, 850, 700 and 600 MHz NMR spectrometers, wet-lab facilities dedicated to in vivo and in vitro protein expression and purification, and state-of-the‑art imaging and biophysics facilities for sample characterization.
joint research unit (CEA-CNRS-UGA), the IBS is made up of 21 research groups, each offering a multidisciplinary approach at the frontiers of biology, physics and chemistry, in line with the IBS's 3 main lines of research. Nearly 300 people work at IBS as researchers, post‑docs, PhD students, engineers and technicians in a multicultural and international environment.

The postdoctoral researcher recruited will join the NMR of Large Assemblies group, which develops and applies advanced isotope labelling and NMR methods to study the structure, dynamics and mechanisms of large protein complexes. The group headed by Dr. Boisbouvier comprises a research director, three engineers, three post‑docs and four PhD students.

• Candidates must hold a PhD in chemistry, biochemistry or structural biology (or a related discipline) and have experience of protein expression and purification as well as experience in the protein structural and dynamics studies using solution NMR spectroscopy.
• Ability to conceptualise, creativity, scientific curiosity, sense of innovation.
• Good communication (written/oral) and teaching skills.
• Team spirit.
• C2 level English (written/oral)