Post-Doctoral Fellow

Université Paris Cité; France; Sur place; EUR 30 000 - 40 000; Plein temps

Résumé du poste

A renowned research institution in France seeks a post-doctoral fellow for the Chromosome Dynamics team at IPS2. The ideal candidate will hold a Ph.D. and possess experimental and computational skills in genome organization and gene expression regulation, with a strong knowledge of molecular biology. Additionally, proficiency in English is required. This full-time position is situated in Gif Sur Yvette, aiming to unravel the dynamics of chromatin in plant development.

Qualifications

• Ph.D. required for the post-doctoral fellowship.
• Excellent proficiency in English is essential.
• Knowledge of molecular biology is necessary.

Responsabilités

• Study genome organization and its influence on gene expression regulation.
• Use experimental and computational methods to conduct research.
• Analyze data from Hi-C, HiChIP, and other molecular techniques.

Connaissances

Experimental approaches

Computational approaches

Hi-C

HiChIP

ChIP-seq

DNA methylation analysis

RNA-seq

Molecular biology

English proficiency

Formation

Ph.D. or equivalent

Description du poste

Organisation/Company Université Paris Cité Department IPS2 Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions Postdoc Positions Country France Application Deadline 31 Jan 2026 - 16:13 (Europe/Paris) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 15 Dec 2025 Is the job funded through the EU Research Framework Programme? Horizon Europe - ERC Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The post-doctoral fellow will join the "Chromosome Dynamics" team of the Paris‑Saclay Institute of Plant Sciences (IPS2), which aims to understand how chromatin dynamics control plant development and their response to stress. Indeed, plants are sessile organisms that constantly adapt to fluctuations in their environment. They have therefore acquired significant plasticity in the course of evolution, both in terms of physiological responses and development. Plants form new organs throughout their life cycle, thus shaping the entire architecture of their vegetative apparatus according to environmental conditions. This particular mode of development requires mechanisms for robust regulation of key developmental genes, as well as the maintenance of stem cell pools in which genetic and epigenetic information must be stored and faithfully reproduced through cell divisions. Indeed, genetic information is carried by DNA, but how this information is interpreted depends largely on how DNA interacts with histones in chromatin, and how this chromatin is opened to allow access to the transcription machinery. The deposition of post‑translational modifications on histones, the incorporation of histone variants, DNA methylation, non‑coding RNAs and the formation of chromatin loops cooperate in the coordinated activation or repression of large gene sets. Within this framework, the team studies the relationships between gene expression and chromatin organisation in the context of plant development and stress response.

Where to apply

E-mail [e-mail]

Requirements

• Education level: Ph.D. or equivalent.
• Skills/Qualifications: The Chromosome Dynamics group is looking for a post‑doctoral fellow who will use experimental and computational approaches to study genome organisation and its influence on the regulation of gene expression.
• Methods and analyses: Hi‑C, HiChIP, ChIP‑seq, DNA methylation analysis, RNA‑seq and associated computational analyses.
• Knowledge of molecular biology is essential; experience in crop processing is preferred.
• Ideal candidate must be highly ambitious and motivated.
• Language: Excellent proficiency in English.

Work Location(s)

Company/Institute IPS2 – Institute of Plant Sciences, Paris Saclay, Gif-sur-Yvette, 91190, Avenue des Sciences, Geofield. City: Gif Sur Yvette.