Marie Sklodowska Curie Action - Postdoctoral individual Fellowship at IPBS-Toulouse, France (In[...]

euraxess.ec.europa.eu - Jobboard; France; Sur place; EUR 40 000 - 60 000; Plein temps

Résumé du poste

A leading research institute in France is seeking motivated postdoctoral researchers to join their laboratory on a Marie Skłodowska-Curie fellowship. The role focuses on the structural biology of membrane receptors, emphasizing the use of techniques like NMR spectroscopy and protein purification to unravel biomolecular mechanisms. Candidates must hold or expect to obtain a PhD and have experience with membrane proteins. This is an exciting opportunity to work in a vibrant, international research community in Toulouse.

Prestations

Career development support

Vibrant research community

Mentoring for fellowship writing

Qualifications

• Candidates must hold a PhD or expect to obtain it prior to the application deadline.
• Experience in protein expression and purification of membrane proteins.

Responsabilités

• Conduct research on membrane receptors and biomolecular mechanisms.
• Use NMR spectroscopy and biophysical techniques for protein studies.

Connaissances

Protein expression and purification

Experience with membrane proteins

Nuclear Magnetic Resonance (NMR)

Formation

PhD in relevant field

Description du poste

Organisation / Company Centre National de la Recherche Scientifique, Université de Toulouse Department Biology Laboratory Institute of Pharmacology and Structural Biology (Toulouse, France) Is the Hosting related to staff position within a Research Infrastructure? No

The IPBS (Institute of Pharmacology and Structural Biology) is seeking motivated postdoctoral researchers to apply for Marie Skłodowska-Curie fellowships and join our laboratory to carry out their research project.

Research topic

Structural biology of membrane receptors

We aim to decipher biomolecular mechanisms playing key roles in host-pathogen relationships. Our research focuses primarily on human membrane receptors involved in pathogen detection and immune signaling. Leveraging our core expertise in biophysics and NMR spectroscopy, we integrate these methods with complementary structural and functional approaches, with a particular emphasis on the role of protein structural dynamics and on the influence of modulators of the cell environment. By combining a molecular understanding of these targets with ligand-screening techniques, we aim to contribute to the early-stage development of therapeutics against infections, inflammatory diseases, and cancer.

We are looking for a skilled researcher to further our understanding of how extracellular ligand binding to membrane receptors (G protein-coupled receptors and C-type lectin receptors) leads to intracellular events, and how responses differ among sets of related proteins. The researcher will pursue the expression and purification of soluble protein domains and the preparation of full-length proteins in membrane-mimetic environments. They will use NMR spectroscopy, SAXS, and an array of biophysical techniques to probe the functional responses of these proteins at the atomic level.

Keywords

Protein expression and purification - Membrane proteins - Nuclear Magnetic Resonance

Experience / Skills required

• Candidates must hold a PhD or expect to obtain it prior to the application deadline
• Experience in protein expression and purification of membrane proteins

✅ Work at the cutting edge of molecular biology, structural biology, imaging, and omics technologies in Toulouse, France
✅ Join a vibrant international research community, with connections across Toulouse and throughout Europe

✅ Benefit from career development support, including mentoring for fellowship writing, networking, and future job applications

Application Process

Send a detailed CV, a cover letter outlining your research interests and motivation for joining the group, and the names and contact information of at least 2 professional references (potential supporters and mentors) to :

Internal deadline: 15 January 2026

Don’t hesitate to apply now as applications will be reviewed on a rolling basis.

• Expected Starting date: From September 2026 to September 2027 depending on the funding