Biomarker Discovery Research Officer

MIRXES LAB PTE. LTD.; Singapore; On-site; SGD 40,000 - 60,000; Full time

Job summary

A leading molecular diagnostic company in Singapore is seeking a Research Officer for their Profiling and Sequencing team. This role involves executing experiments for high-throughput biomarker discovery, including RNA isolation and RT-qPCR profiling. Candidates should have a Diploma or Degree in a related Science discipline and preferably at least 1 year of molecular biology experience. Strong technical skills and the ability to work independently while thriving in a fast-paced environment are essential. Candidates will support compliance with health and safety policies in a collaborative setting.

Qualifications

• 1+ years of experience in molecular biology preferred.
• Familiarity with ELISA, NGS and RT-qPCR is a plus.
• Proven ability to work independently and in teams.

Responsibilities

• Execute high-throughput biomarker discovery experiments.
• Perform RNA isolation and reverse transcription.
• Conduct nucleic acid extraction and library preparation.
• Maintain accurate inventory of clinical samples.
• Write technical reports and SOPs.

Skills

Molecular biology experience

RT-qPCR profiling

NGS workflows

ELISA

Data analysis

Technical writing

Education

Diploma or Degree in a related Science discipline

Tools

RT-qPCR equipment

NGS sequencing platform

ELISA kit

Job description

MiRXES is a Singapore-headquartered molecular diagnostic company with R&D, manufacturing, and clinical lab operations in Singapore, USA, Japan, and China. We specialize in microRNA technologies and the development, manufacturing, and provision of diagnostic test kits and clinical services. Our mission is to enable early disease detection and provide insights for better patient care by harnessing the power of microRNA to augment traditional testing. Our vision is to be the world's leading developer and provider of accurate, actionable, and affordable microRNA-powered diagnostic tests.

Job Location: Helios (Onsite)

Job Summary

MiRXES Lab is seeking a Research Officer to join our Profiling and Sequencing team. The biomarker team research officer will assist in development and execution of protocols and SOPs to enable high-quality data to be obtained from precious clinical samples.

Roles and Responsibilities

• Precise execution of experiments for high-throughput biomarker discovery using clinical samples.
• miRNA RT-qPCR profiling, including RNA isolation, reverse transcription and qPCR.
• NGS workflows such as nucleic acid extraction, library preparation and sequencing.
• Other technologies either commercially available or developed in-house.
• Keep accurate inventory of the clinical samples.
• Perform literature search, design, and conduct experiments for the development, optimization and validation of biomarker discovery technologies.
• Data collection and organization for downstream data analysis.
• Maintain accurate experimental records.
• Perform other experiments such as ELISA, Western blotting etc. as required to support biomarker discovery.
• Write and/or support preparation of technical reports, SOPs and documents.
• Validate procedures for instrument testing, quality control and generate final reports.
• Provide experimental and technical support to internal and external stakeholders whenever necessary.
• Inventory maintenance and procurement of consumables and reagents.
• Provide support for bio-banking activities, if necessary, such as blood processing, sample registration.
• Provide support for compliance of health and safety policies.

Desired Skills & Competencies

• Diploma or Degree in a related Science discipline.
• Preferably with at least 1 year of molecular biology experience.
• Experience in ELISA, NGS and RT-qPCR is a plus.
• Results oriented, with integrity and dependability with a strong sense of prioritization.
• Able to develop in-depth technical troubleshooting skills and exercise sound judgment, making decisions based on accurate and timely analyses.
• Ability to plan ahead and provide insights and alternatives for contingency.
• Good verbal communication, interpersonal and team skills.
• Demonstrate ability and confidence to work independently as well as within a team.
• Thrive in fast-paced environment where teamwork is essential to success.

This position is based in Singapore.

We appreciate your interest in the above-mentioned position, however, due to overwhelming response, only shortlisted candidates will be contacted.