Principal Statistician (HEOR)

Red Nucleus; United Kingdom; Remote; GBP 60,000 - 80,000; Full time

Job summary

A life sciences consulting firm is expanding its team by hiring a Principal HEOR Statistician to lead advanced statistical analysis and provide insights for decision-making. This role involves designing experiments, developing models, and conveying complex findings to stakeholders. The ideal candidate should possess a Master’s or Ph.D., demonstrate proficiency in statistical software, and have over 5 years of experience in applying statistical methodologies. There is a remote work option available for candidates in various regions including the UK.

Qualifications

• 5+ years of experience in statistical analysis and modeling in a business or research setting.
• Proven track record of applying advanced statistical methods to real-world problems.

Responsibilities

• Lead advanced statistical analysis for HEOR and real-world evidence.
• Ensure data integrity and accuracy through validation and cleaning.
• Prepare detailed protocols, reports, dashboards for audiences.
• Provide guidance and mentorship to junior statisticians.

Skills

Statistical software proficiency (R, SAS, Python)

Data visualization tools proficiency (Tableau, Power BI)

Strong analytical skills

Problem-solving abilities

Excellent communication skills

Education

Master’s or Ph.D. in Statistics, Mathematics, Data Science, or a related field

Job description

Red Nucleus is expanding and hiring a Principal HEOR Statistician. This role can be remote based in the US, Canada, or the UK.

COMPANY DESCRIPTION:

Red Nucleus is a premier provider of global solutions for R&D, Medical Affairs, Value & Evidence, and Commercial teams within biopharmaceutical, medical device, and diagnostics industries. Squarely focused on the life sciences industry for more than 30 years, Red Nucleus takes pride in our long-term relationships with industry leaders, as well as our strategic partnerships with innovative startups. We are focused on developing thoughtful, high-quality solutions that are in accordance with each client’s unique culture and needs. Our clients trust us to build impactful, award-winning programs that deliver actionable insights and measurable results.

Job Overview

The Principal Statistician will lead advanced statistical analysis for HEOR, meta-analysis and indirect treatment comparisons and real-world evidence analyses to support data-driven decision-making in the HEOR business unit. This role involves designing experiments, developing predictive models, and providing actionable insights to improve business strategies and outcomes. The ideal candidate is highly skilled in statistical methodologies, data interpretation, and communication of complex findings to non-technical stakeholders.

Responsibilities

• Statistical Analysis & Modeling
  • Apply statistical methods commonly used in HEOR, including survival analysis, time-to-event modeling, mixed-effects models, generalized linear models
  • Conduct analyses of clinical trial IPD, real-world evidence (claims, registry, EHR), and patient-reported outcomes
  • Carry out indirect treatment comparisons (including the more advanced techniques such as MAIC, STC and ML-NMR)
• Data Management & Quality
  • Ensure data integrity and accuracy through rigorous validation and cleaning processes.
  • Develop code library that is fully validated and ready to use
  • Implement automation where that is relevant and leads to better quality and improved results
  • Develop programmes/algorithms that can be used by more junior resources to perform relatively routine tasks related to the HEOR statistics and are already used by many of our competitors (e.g. survival curve reading and extrapolation, etc.)
  • Work with Modeling team to understand the evolving need of inputs
• Reporting & Communication
  • Prepare detailed protocols, reports, dashboards, and presentations for technical and non-technical audiences.
  • Translate statistical findings into clear, actionable insights for business leaders.
• Leadership & Mentorship
  • Provide guidance and mentorship to junior statisticians .
  • Stay current with emerging statistical techniques and tools
  • Share best practices with the team.

Education

• Master’s or Ph.D. in Statistics, Mathematics, Data Science, or a related field.

Experience

• 5+ years of experience in statistical analysis and modeling in a business or research setting.
• Proven track record of applying advanced statistical methods to real-world problems.

Skills & Abilities

• Proficiency in statistical software (e.g., R, SAS, Python) and data visualization tools (e.g., Tableau, Power BI).
• Strong understanding of probability theory, hypothesis testing, and experimental design.
• Excellent analytical, problem-solving, and critical-thinking abilities.
• Strong communication skills to convey complex concepts clearly.