Postdoctoral Researcher

MRC Laboratory of Molecular Biology; Newtown; On-site; GBP 30,000 - 40,000; Full time

Job summary

A leading biomedical research institute in the UK is recruiting a Postdoctoral Researcher to investigate the mechanism of co‑transcriptional splicing. This role focuses on understanding the crosstalk between transcription and splicing machineries through biochemical and structural approaches, specifically cryo‑EM. Ideal candidates will hold a PhD in biological sciences and possess skills in structural biology and protein purification. Exceptional communication and teamwork skills are essential. The organization offers a collaborative work environment and numerous benefits, including extensive holiday entitlement and professional development opportunities.

Benefits

On-site parking

Cycle enclosures

Excellent public transport links

Staff restaurant with roof terrace

Access to Campus nursery

Sports and social facilities

Defined benefit pension scheme

Holiday entitlement of 40.5 days

Generous employee discount scheme

Training and development opportunities

Qualifications

• PhD completed within 6 months is acceptable.
• Strong background in structural biology, biochemistry, or cell biology required.
• Experience in protein purification and mammalian cell work desirable.

Responsibilities

• Investigate the mechanism of co‑transcriptional splicing.
• Understand crosstalk between transcription and splicing machineries.
• Utilize biochemical and structural approaches focusing on cryo‑EM.

Skills

Strong background in structural biology

Biochemistry

Cell biology

Protein purification

Mammalian cell work

Good communication skills

Education

PhD in biological sciences

Job description

Position Overview

We are recruiting a Postdoctoral Researcher to join Dr Suyang Zhang's group to investigate the mechanism of co‑transcriptional splicing. The project aims to understand the mechanism of crosstalk between the transcription and splicing machineries using a combined biochemical and structural approach with a focus on cryo‑EM and isolation from endogenous sources.

Responsibilities & Qualifications

The successful candidate should have a PhD in biological sciences or have completed a PhD within 6 months, and a strong background in structural biology, biochemistry or cell biology. Experience in protein purification and mammalian cell work are desirable. The candidate should have worked independently and have good communication skills for teamwork.

Benefits & Working Conditions

The LMB has a collaborative working culture and state‑of‑the‑art building based on the Cambridge Biomedical Campus. We have on‑site parking, cycle enclosures and excellent public transport links to the site. We have a staff restaurant with roof terrace and access to a Campus nursery and sports and social facilities. You will be eligible to join our defined benefit pension scheme, a holiday entitlement of 40.5 days (including bank holidays and privilege days) and a generous employee discount scheme. We are also committed to providing training and development opportunities including support towards role‑related qualifications. Further information about the benefits available can be found at http://www.discover.ukri.org/benefits-of-working-at-ukri.