Postdoctoral Research Associate in Transporter Structural Biology & Signalling Mechanisms

University of Oxford; Oxford; On-site; GBP 30,000 - 45,000; Full time

Job summary

A prestigious university in Oxford is seeking a highly motivated Postdoctoral Research Associate to support groundbreaking research on Solute Carrier Biology. This full-time role involves managing experiments, data analysis, and collaborating with diverse partners. Ideal candidates will hold a PhD with skills in structural biology, biophysics, and cellular imaging. The position offers an excellent pension scheme, generous leave, and various childcare services, with an initial contract of up to 3 years.

Benefits

Contributory pension scheme

38 days annual leave

Childcare services

Family leave schemes

Cycle loan scheme

Social and sports clubs membership

Discounted bus travel

Qualifications

• PhD in relevant field (biochemistry, molecular biology, etc.).
• Experience with structural biology techniques and data analysis.
• Ability to work independently and collaboratively on research projects.

Responsibilities

• Manage research and lead experimental design for the project.
• Collect and analyze cryo-EM and super-resolution imaging data.
• Collaborate with partners and supervise students.

Skills

Structural biology

Biophysics

Cell biology

Cryo-EM

Cellular imaging

Education

PhD in relevant field

Tools

Advanced mass spectrometry

Protein production platforms

Job description

Postdoctoral Research Associate – Solute Carrier Biology

We are seeking a talented and highly motivated Postdoctoral Research Associate to join Professor Simon Newstead's laboratory, supporting a Wellcome Discovery Award on Solute Carrier Biology: Linking Transport and Signalling in the Cell. This is an exceptional opportunity to work at the interface of structural biology, biophysics and cell biology, exploring the architecture and function of membrane protein complexes involved in organelle homeostasis, metabolic regulation and organellar signalling pathways.

You will be based in the Department of Biochemistry and the Kavli Institute for Nanoscience Discovery, providing ready access to state-of-the-art facilities, including high-end cryo-EM, advanced protein production platforms, mass spectrometry (native/lipidomic/proteomic) and cellular imaging (super resolution/electron tomography). Importantly, you will contribute to cutting-edge research with clear translational relevance in metabolic diseases, drug pharmacokinetics and tissue homeostasis.

Responsibilities

• Manage your own research within the project, leading experimental design, protein production, purification, and structural, biophysical and cellular characterisation of solute carrier complexes.
• Independently collect and analyse cryo-EM and super-resolution imaging data, adapt and develop new protocols, generate nanobodies and contribute to research publications, grant applications and presentations at national and international conferences.
• Collaborate closely with internal and external partners and play a valuable role in advising colleagues and supervising students.

This full-time fixed-term post is funded by the Wellcome Trust for up to 3 years in the first instance. The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

Share information on what the ideal candidates look like including the qualifications, skills and experience required for the role. Refer for specific information required if a Skilled Worker visa application is required.

What We Offer

• An excellent contributory pension scheme
• 38 days annual leave
• A comprehensive range of childcare services
• Family leave schemes
• Cycle loan scheme
• Membership to a variety of social and sports clubs
• Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.