Lead Scientist Drug Discovery

Taylorollinson; Macclesfield; On-site; GBP 58,000 - 65,000; Full time

Job summary

A leading collaborative drug discovery company is seeking a Lead Scientist to join their Cellular Sciences Team in Macclesfield. The successful candidate will have extensive experience in drug discovery, hold a PhD or Master’s in a biological discipline, and possess strong leadership skills. Responsibilities include managing a team of scientists and driving complex drug discovery projects. The package includes a competitive salary of approximately £58,000 - £65,000 along with benefits, and requires the right to work in the UK without visa sponsorship.

Benefits

Competitive salary

Benefits package

Qualifications

• Must have a PhD or Master’s in a biological discipline.
• Proven track record of managing drug discovery projects.
• Extensive experience with various microscopy techniques.

Responsibilities

• Manage a team of scientists for drug discovery projects.
• Lead and direct drug discovery and disease research.
• Create and edit cell lines using molecular biology techniques.

Skills

Drug discovery experience

Leadership experience

Confocal microscopy

Live cell imaging

Cell line engineering

Communication skills

Education

PhD or Master’s in a biological discipline

Tools

CRISPR

High content imaging

Job description

Lead Scientist - Drug Discovery

Location: Cheshire

Sector: Drug Discovery

Salary: c£58,000 - £65,000 depending on experience

Contact: Full Time and Permanent opportunity

Visa: Sponsorship is not available for this role - you must have indefinite right to work in the UK.

Overview: Our client is a leading company, offering research services to the Drug Discovery sector. They collaborate with lead researchers and organisations to enhance the understanding of immunological, oncological, neurological and other disease areas. They are offering an exciting opportunity for an enthusiastic and hard‑working individual to join their Cellular Sciences Team as a Lead Scientist within advanced microscopy and molecular biology. If you have built an extensive career in drug discovery and are looking to work on exciting pre‑clinical and ex‑vivo drug discovery projects and want to further your career, then this could be the opportunity you have been waiting for.

Role

This is a role for highly experienced Scientists with many years' experience in drug discovery. They will hold a PhD (or Master's) in a biologically focused discipline and an extensive track record of leadership positions within drug discovery (industry preferred). This is a technical role where you will still spend some of your time at the bench, but you will be responsible for delivering and strategizing projects through to completion by managing a team of scientists.

Responsibilities

• Managing a team of scientists to complete complex drug discovery projects
• Leading, proposing and directing projects relating to drug discovery and disease research
• Editing and creating cell lines through transduction, CRISPR and other molecular biology techniques
• Using various light microscopy techniques including super resolution microscopy, high content imaging, confocal imaging, multi-photon imaging, live cell imaging e.g. Incucyte etc.
• Working on complex cellular models, tissues, fixed cells and live cell imaging projects
• Establishing strong collaborations and supporting business development as a technical expert to showcase the value of imaging projects in drug discovery
• Liaising with external collaborators to provide project milestone updates and drive further research initiatives
• Keeping up to date with the latest technological changes and suggesting new tools to be used internally

Skills and Experience

• A PhD or Master’s in a biological discipline (essential)
• Proven track record of delivering high-impact drug discovery projects on-time and within budget (essential)
• Proven line management experience (essential)Extensive drug discovery experience through discovery and preclinical phases, with experience in developing in vitro biological assays (essential)
• Many years of post-PhD experience in running and using various types of light microscopy including several of the following: Confocal microscopy, Super Resolution (PTM, SIM, STED, STORM, PALM etc), live cell imaging, high content imaging (HCI) (essential)
• Strong cell line editing/engineering experience (CRISPR, lentiviral transduction, transfection etc) (CRISPR is essential, others desired)
• Previous experience working with industry, either in a company or in close collaboration with an industry partner (essential)
• Understanding and experience in the disease research or drug discovery sector (essential)
• Strong network in drug discovery and collaboration experience with other experts in the field (essential)
• Experience in working with nanomedicines such as LNPs, nanoparticle or liposomes (desired)
• Excellent communication, multi-tasking skills (essential)
• Must have indefinite right to work in the UK without need for visa sponsorship (essential)

Package

Being a leading collaborative drug discovery company, our client offers the chance to be part of a growing organisation on a permanent basis, with a competitive salary and benefits package.